Author

D. Cicka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Wahafu· 2 shared C. Shu· 2 shared D. Fan· 2 shared H. Fu· 2 shared Q. Niu· 2 shared S. Doyle· 2 shared T. Owonikoko· 2 shared W. Zhou· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Wahafu

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2 papers

Recent·Most cited

Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

X. Mo, Q. Niu, A. A. Ivanov, Y. H. Tsang, C. Tang, C. Shu, A. Wahafu, S. Doyle, D. Cicka, X. Yang, D. Fan, M. A. Reyna, L. A. D. Cooper, C. S. Moreno, W. Zhou, , H. Fu

The paper identifies mutation-directed neo-protein-protein interactions in cancer using a high-throughput screening platform, revealing therapeutic opportunities through neo-interaction rewiring.

bioRxiv · Oct 3, 2021Cancer Biology

Pharmacological rescue of tumor intrinsic STING expression and immune response in LKB1-mutant lung cancer via the IAP-JAK regulatory axis

C. Shu, R. Jin, Q. Niu, D. Cicka, S. Doyle, A. Wahafu, D. Fan, X. Zheng, Y. Du, A. Ivanov, D. Doxie, K. Dhodapkar, J. Carlisle, T. Owonikoko, S. Ramalingam, , H. Fu

The paper identifies IAP inhibitors as sensitizers that restore immune response in LKB1-mutant lung cancer by reactivating the STING pathway and enhancing immune infiltration.

bioRxiv · Sep 17, 2021 · PreprintCancer Biology