Author

D. Drasdo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Assay:imaging· 1

Frequent Co-Authors

S. Hoehme· 2 shared A. Damle-Vartak· 1 shared A. Friebel· 1 shared A. Ghallab· 1 shared B. Begher-Tibbe· 1 shared B. Sun· 1 shared C. Gao· 1 shared C. Hedberg· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPhysiology

S. Hoehme

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ECM1 Attenuates Hepatic Fibrosis by Interfering with Mediators of Latent TGF-β1 Activation

F. Link, Y. Li, J. Zhao, S. Munker, W. Fan, Z. Nwosu, Y. Yao, S. Wang, C. Huang, S. Hammad, R. Liebe, H. Liu, C. Shao, C. Gao, B. Sun, , S. Wang

This study shows ECM1 prevents hepatic fibrosis by inhibiting TGF-β1 activation, with implications for developing safe anti-fibrotic therapies.

bioRxiv · Dec 12, 2023Cell Biology

Intravital multi-modal flux analysis reveals the transport mechanism of bile acids through hepatic microconduits

N. Vartak, G. Guenther, F. Joly, A. Damle-Vartak, G. Wibbelt, J. Fickel, S. Jörs, B. Begher-Tibbe, A. Friebel, K. Wansing, A. Ghallab, M. Rosselin, N. Boissier, I. Vignon-Clementel, C. Hedberg, , J. G. Hengstler

The paper develops two techniques to quantify bile acid transport in liver microdomains, revealing diffusion in canaliculi and advection in ducts.

bioRxiv · Jun 4, 2020Physiology

Quantifying the mechanics and growth of cells and tissues in 3D using high resolution computational models.

P. Van Liedekerke, J. Neitsch, T. Johann, E. Warmt, I. Gonzales Valverde, S. Grosser, S. Hoehme, J. Kaes, D. Drasdo

The paper develops a 3D high-resolution cell-based model to study liver regeneration after drug-induced hepatocyte depletion, finding that migration forces required for tissue closure are lower than predicted by center-based models.

bioRxiv · Jan 22, 2019 · PreprintBioengineering