Author

E. Krystofiak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 4 Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 5 Organism:mouse· 5 Research Focus:cell type annotation· 4 Organism:human· 4 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2

Frequent Co-Authors

A. M. Weaver· 2 shared B. Barman· 2 shared J. B. Silverman· 2 shared M. J. Tyska· 2 shared A. A. Ghelmansaraei· 1 shared A. Cooley· 1 shared A. E. Sewell· 1 shared A. Sugiura· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. M. Weaver

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Intestinal tuft cells assemble a cytoskeletal superstructure composed of co-aligned actin bundles and microtubules

J. B. Silverman, E. Krystofiak, L. R. Caplan, K. S. Lau, M. J. Tyska

This study uses advanced microscopy to reveal the ultrastructural organization of tuft cell cytoskeleton, showing co-aligned actin bundles and microtubules.

bioRxiv · Mar 19, 2024Cell Biology

Mammalian orthoreovirus can exit cells in extracellular vesicles

S. C. Smith, E. Krystofiak, K. Ogden

This study shows mammalian orthoreovirus exits cells via extracellular vesicles and free particles, with EVs providing strain- and cell-type-specific protection from neutralization.

bioRxiv · Aug 29, 2023Microbiology

Culture conditions greatly impact the levels of vesicular and extravesicular Ago2 and RNA in extracellular vesicle preparations.

L. Jimenez, B. Barman, Y. J. Jung, L. N. Cocozza, E. Krystofiak, C. E. Saffold, K. C. Vickers, J. T. Wilson, T. R. Dawson, A. M. Weaver

The paper investigates how culture conditions affect the levels of Ago2 and RNA in extracellular vesicles, finding that serum and cell state influence their presence.

bioRxiv · Jun 21, 2023Cancer Biology

Adhesion-based capture stabilizes nascent microvilli at epithelial cell junctions

C. S. Cencer, J. B. Silverman, L. Meenderink, E. Krystofiak, B. A. Millis, M. J. Tyska

This study shows that intermicrovillar adhesion complexes stabilize nascent microvilli at epithelial cell margins through transjunctional interactions, leading to their accumulation in medial regions.

bioRxiv · Mar 8, 2023Cell Biology

Radiation-Induced Autophagy Regulates the Fibroblast Mitochondrial Stress Response and Crosstalk with Triple-Negative Breast Cancer Cells

K. C. Corn, S. E. Martello, V. K. Menon, L. S. Britto, K. K. Simmons, Y. K. Mohamed, Y. I. Ivanova, A. A. Ghelmansaraei, S. A. Weidenbach, T. Zhu, E. Krystofiak, J. D. Young, V. Gama, M. Rafat

This study shows that radiation-induced autophagy in fibroblasts alters their mitochondrial stress response, promoting an aggressive phenotype in triple-negative breast cancer cells.

bioRxiv · May 17, 2022Cancer Biology

Dysregulated Transferrin Receptor Disrupts T Cell Iron Homeostasis to Drive Inflammation in Systemic Lupus Erythematosus

K. Voss, A. Young, K. N. Gibson-Corley, A. E. Sewell, E. Krystofiak, J. H. Bashum, W. N. Beavers, A. Sugiura, E. P. Skaar, M. J. Ormseth, J. Rathmell

This study shows that dysregulated CD71 in T cells increases iron uptake, disrupts mitochondrial function, and drives inflammation in SLE, with CD71 blockade improving outcomes.

bioRxiv · Nov 25, 2021 · PreprintImmunology

Trypanosoma brucei Tim50 Plays a Critical Role in Cell Cycle Regulation and Parasite Infectivity

A. Tripathi, U. K. Singha, A. Cooley, T. Gillyard, E. Krystofiak, S. Pratap, J. Davis, M. Chaudhuri

This study shows that TbTim50 is essential for mitochondrial function, kDNA replication, and cell cycle regulation in Trypanosoma brucei, and its depletion reduces parasite infectivity.

bioRxiv · Apr 26, 2021Cell Biology

Biogenesis of RNA-containing extracellular vesicles at endoplasmic reticulum membrane contact sites

B. Barman, J. Ping, E. Krystofiak, R. Allen, N. Prasad, K. Vickers, J. G. Patton, Q. Liu, A. M. Weaver

This study identifies VAP-A as a key regulator of RNA-containing extracellular vesicle biogenesis and shows its role in miR-100 transfer and tumor formation.

bioRxiv · Dec 4, 2020 · PreprintCell Biology