Author

E. Poppleton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:experimental assay· 3 Approach:deep learning· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

P. Sulc· 4 shared N. Stephanopoulos· 2 shared Y. Xu· 2 shared A. Doherty· 1 shared A. Prasad· 1 shared F. Zhang· 1 shared H. Liu· 1 shared H. Yan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersBioengineering

P. Sulc

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IgG-inspired, multivalent protein-DNA nanostructures for high-affinity, tunable, and reversible binding to biomolecular targets

R. Zheng, Y. Xu, A. Prasad, M. Liu, Z. Wan, J. Jiang, X. Zhou, R. M. Porter, M. Sample, E. Poppleton, J. Procyk, H. Liu, A. Doherty, P. Nyaupane, Y. Li, , N. Stephanopoulos

This paper designs and tests a DNA-based synthetic antibody (nano-synbody) that binds SARS-CoV-2 spike proteins with high affinity and reversibility through multivalency.

bioRxiv · Sep 18, 2023 · PreprintBioengineering

DNA Nanostructure-Guided Assembly of Proteins into Programmable Shapes

Q. Lu, Y. Xu, E. Poppleton, K. Zhou, P. Sulc, N. Stephanopoulos, Y. Ke

This paper describes a method using DNA origami to guide the assembly of protein-DNA conjugates into programmable nanostructures with controlled stoichiometry and geometry.

bioRxiv · Aug 7, 2023Bioengineering

A rhythmically pulsing leaf-spring nanoengine that drives a passive follower

M. Centola, E. Poppleton, M. Centola, J. Valero, P. Sulc, M. Famulok

This paper describes a DNA-nanomachine that performs rhythmic pulsing motion driven by chemical energy and couples it to a passive follower unit.

bioRxiv · Dec 22, 2021 · PreprintBiophysics

Design, optimization, and analysis of large DNA and RNA nanostructures through interactive visualization, editing, and molecular simulation

E. Poppleton, J. Bohlin, M. Matthies, S. Sharma, F. Zhang, P. Sulc

The paper introduces oxView and open-source tools for visualizing and analyzing large DNA/RNA nanostructures simulated with oxDNA, enabling design, optimization, and structural analysis.

bioRxiv · Jan 24, 2020Biophysics