A Host-Harbored Metabolic Susceptibility of Coronavirus Enables Broad-Spectrum Targeting
H. Fang, Y. Wang, L. Liu, K. Cheng, P. Li, Y. Tan, X. Hao, M. Mei, X. Xu, Y. Yao, F. Zan, L. Wu, Y. Zhu, B. Xu, D. Huang, , X.-W. Chen
The paper identifies a host metabolic pathway essential for coronavirus replication and shows that inhibiting it with Propranolol has broad antiviral effects.
bioRxiv · Dec 7, 2022 · PreprintCell Biology