G. Arora

NK cell-induced damage to P. falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG

This study shows NK cells lyse P. falciparum-infected erythrocytes via ADCC, releasing parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG.

The Lyme Disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector

This study identifies a tick metabolic pathway involving ISARL that Borrelia burgdorferi exploits to establish infection, suggesting a mechanism for manipulating host metabolism.

Kinetic tracking of Plasmodium falciparum antigen presentation reveals determinants of protein export and membrane insertion

The paper introduces RISE, a method to track antigen exposure in malaria parasites, revealing factors influencing protein export and membrane insertion.

Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype

This paper shows that repeated Plasmodium falciparum infections reprogram human monocytes to a regulatory phenotype, reducing inflammatory responses during subsequent infections.

JAK Inhibitors Suppress Colon Cancer Cachexia-Associated Anorexia and Adipose Wasting in Mice

This study shows JAK inhibitors reduce cachexia-associated anorexia and adipose wasting in colon cancer models by blocking cytokine-induced pathways.

NK cells inhibit Plasmodium falciparum growth in red blood cells via antibody dependent cellular cytotoxicity

The paper shows that antibodies from malaria-exposed individuals activate NK cells to lyse infected red blood cells and inhibit parasite growth via ADCC.