G. Grant

Microfluidic analysis reveals ROCK2 regulation of endothelial cilia is essential for blood vessel lumen formation and vascular integrity

This study shows ROCK2 regulates endothelial cilia, which is critical for blood vessel lumen formation and vascular integrity.

Pulmonary Matrix Derived Hydrogels from Patients with Idiopathic Pulmonary Fibrosis Induce a Proinflammatory State in Lung Fibroblasts In Vitro

This study uses patient-derived hydrogels to show IPF fibroblasts exhibit increased inflammation and altered contractility in 3D culture compared to 2D.

The Presence of the Temporal Horn Exacerbates the Vulnerability of Hippocampus during Head Impacts

This study uses computational models to show that the temporal horn increases hippocampal vulnerability during head impacts by increasing strain and strain rate in specific subfields.

Towards a comprehensive delineation of white matter tract-related deformation

This study introduces three new tract-related strain measures to improve concussion prediction in finite element head models by analyzing white matter deformation during impacts.

White matter tract-oriented deformation is dependent on real-time axonal fiber orientation

This study shows that real-time axonal fiber orientation during impact affects tract-oriented strain in white matter, increasing deformation magnitude and distribution.

A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes

This study identifies a specific RSV genomic sequence that regulates the generation of copy-back defective viral genomes, showing that cbDVG formation is not random and can be manipulated.

Circadian control of lung inflammation in influenza infection

This study shows that circadian rhythms affect lung inflammation during influenza infection by influencing immune cell composition rather than viral replication.

High-resolution wide-field human brain tumor margin detection and in vivo murine neuroimaging

This paper introduces SM-OCT, a high-resolution neuroimaging technique that detects brain tumor margins in vivo and ex vivo with endogenous contrast.