Author

G. A. FitzGerald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

G. R. Grant· 3 shared S. Sengupta· 2 shared S. Y. Tang· 2 shared A. B. Reddy· 1 shared A. Babu· 1 shared A. Cartier· 1 shared A. Culbertson· 1 shared A. Inoue· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersPharmacology & Toxicology

G. R. Grant

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Engineered high-density lipoprotein particles that chaperone bioactive lipid mediators to combat endothelial dysfunction and thromboinflammation

S. Swendeman, D. Lin, S. Guo, A. Culbertson, A. Kuo, M. Levesque, A. Cartier, T. Seno, A. Schmaier, S. Galvani, A. Inoue, S. Parikh, G. A. FitzGerald, M. Liao, R. Flaumenhaft, T. Hla

This paper constructs engineered HDL-like particles that chaperone bioactive lipids to reduce inflammation and endothelial dysfunction.

bioRxiv · Feb 14, 2022 · PreprintBiochemistry

Circadian regulation of lung repair and regeneration

A. Naik, K. Forrest, Y. Issah, U. Valekunja, A. B. Reddy, E. Hennessy, T. Brooks, A. Babu, M. Morley, G. R. Grant, G. A. FitzGerald, A. Sehgal, G. S. Worthen, D. B. Frank, E. E. Morrisey, S. Sengupta

This study shows that the circadian clock regulates lung repair and regeneration independently of inflammation, identifies the Wnt/β-catenin pathway as a mediator, and links poor circadian rhythms to worse lung infection outcomes.

bioRxiv · Nov 20, 2021Cell Biology

Myeloid cell mPGES-1 mediates inflammatory pain hypersensitivity in mice.

L. Chen, G. Yang, D. P. Cormode, A. Saigal, S. Madhavan, L. L. Mazaleuskaya, G. R. Grant, G. A. FitzGerald, T. Grosser

This study shows that myeloid cell mPGES-1 is the main source of PGE2 in inflammatory pain hypersensitivity in mice, suggesting it as a target for new pain therapies.

bioRxiv · Jan 31, 2020 · PreprintPharmacology & Toxicology

Sex dependent compensatory mechanisms to preserve blood pressure homeostasis in PGI2 receptor deficient mice

S. Y. Tang, S. T. Anderson, H. Meng, D. Sarantopoulou, E. Ricciotti, E. J. Hennessy, G. R. Grant, G. A. FitzGerald

This study investigates sex-dependent compensatory mechanisms in blood pressure regulation in PGI2 receptor deficient mice under hyperlipidemic and high salt conditions.

bioRxiv · Jan 27, 2020Pharmacology & Toxicology

Circadian control of lung inflammation in influenza infection

S. Sengupta, S. Y. Tang, J. Devine, S. Nayak, S. Zhang, A. Valenzuela, C. B. Lopez, G. Grant, G. A. FitzGerald

This study shows that circadian rhythms affect lung inflammation during influenza infection by influencing immune cell composition rather than viral replication.

bioRxiv · Aug 21, 2018Immunology