G. Kumar

Acinetobacter baumannii DacC influences cell shape, biofilm formation, and physiological fitness by manifesting DD-carboxypeptidase and β-lactamase dual-enzyme activities

This study identifies DacC in Acinetobacter baumannii as a dual-enzyme with DD-carboxypeptidase and β-lactamase activities that affect cell shape, biofilm formation, and antibiotic susceptibility.

Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits

This study deletes Pf prophages from P. aeruginosa isolates and examines their impact on quorum sensing, biofilm formation, and virulence traits.

Genomic perspectives of SARS CoV-2 in liver disease patients with its clinical correlation: A single centre retrospective study

This study compares the mutational and clinical profiles of liver disease patients infected with different SARS CoV-2 variants, finding higher mortality risk and specific genetic mutations associated with adverse outcomes.

A specific mesh-like organization of human septin octameric complex drives membrane reshaping and curvature sensitivity

The paper investigates the organization and function of human septin octameric complexes at membranes, finding they form a mesh-like structure that drives membrane curvature sensitivity and reshaping.

Human-Sloth Bear (Melursus ursinus) Conflicts in Nawada Forest Division, Nawada, Bihar, India

This study examines sloth bear attacks in Nawada Forest Division, India, identifying seasonal and activity-related patterns in human casualties.

Toll-like receptor 4 signaling in osteoblasts is required for load-induced bone formation in mice

This study shows that TLR4 in osteoblasts is necessary for load-induced bone formation by regulating NGF-TrkA signaling in mice.

Data Driven Control of Vagus Nerve Stimulation for the Cardiac System

This paper develops a data-driven control system for optimizing vagus nerve stimulation parameters in closed-loop control of the rat cardiac system.

Barrier-free liquid condensates of nanocatalysts as effective concentrators of catalysis

This study demonstrates barrier-free liquid condensates of nanocatalysts that enhance catalytic efficiency through molecular confinement without physicochemical barriers.

Phase Separation of Shell Protein and Enzyme: An Insight into the Biogenesis of a Prokaryotic Metabolosome

This study investigates how environmental factors like ionic strength and macromolecular crowding drive the phase separation of shell proteins and enzymes in prokaryotic microcompartments, enhancing enzyme activity.

Membrane remodeling due to mixture of multiple curvature proteins

This study extends a mesoscopic membrane model to simulate how multiple curvature proteins interact to deform membranes, revealing how their mixtures influence vesicle morphology and cargo sorting.

Horizontal transfer of a conserved npc-2 like effector gene in rust fungi that suppresses cell death in plants

The paper identifies a horizontally transferred NPC2-like effector gene from rust fungi that suppresses plant cell death by lipid binding, showing functional conservation with animal NPC2 proteins.

Glby, is a PBP with β-lactamase activity and is required for in vivo viability of M. abscessus

This study identifies Glby, a PBP with β-lactamase activity essential for M. abscessus viability, and suggests it as a potential therapeutic target.

Human gut Bacteroides uniformis utilizes mixed linked β- glucans via an alternativestrategy

This study identifies a novel mechanism by which Bacteroides uniformis utilizes mixed linked β-glucans through a combination of GH-16 and GH-3 enzymes.

Deformation of membrane vesicles due to chiral surface proteins

This study uses Monte-Carlo simulations to examine how chiral surface proteins influence the shape and orientation of deformable membrane vesicles.

Confined filaments in soft vesicles - case of sickle red blood cells

The paper studies shape deformations of red blood cells containing HbS fibers using elasticity and polymer models, finding that confinement leads to multipolar shapes and helical conformations.

Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria

This paper determines the structure of TagA, a glycosyltransferase involved in wall teichoic acid biosynthesis, and reveals its mechanism of catalysis and regulation by membrane interactions.

Pupation site preference selection in Drosophila jambulina

This study investigates pupation site preference in Drosophila jambulina larvae under different temperatures and identifies a genetic basis for this behavior.