G. Yeo

Proteomic discovery of chemical probes that perturb protein complexes in human cells

This study develops a proteomic strategy to identify chemical probes that perturb protein complexes in human cells by analyzing electrophilic compounds' effects on protein interactions.

Selecting Student-Authored Questions for Summative Assessments

This study shows that training students to write multiple-choice questions results in high-quality questions suitable for summative assessments, comparable to those written by experts.

Molecular determinants and heterogeneity of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing

The paper uses single-cell RNA sequencing to study CD8+ T cell differentiation during infection, revealing molecular determinants and functional heterogeneity in tissue-resident memory cells.

Active protein neddylation or ubiquitylation is dispensable for stress granule dynamics

This study shows that active ubiquitylation or neddylation is not required for stress granule dynamics, as inhibitors of these processes do not affect SG formation or dissolution.

Proximity labeling reveals an extensive steady-state stress granule interactome and insights to neurodegeneration

The paper identifies over 100 novel stress granule proteins using proximity labeling and shows they form a dense interaction network, with implications for neurodegeneration.