M. Du

The Genomes of Nematode-Trapping Fungi Provide Insights into the Origin and Diversification of Fungal Carnivorism

This study compares the genomes of nematode-trapping fungi and non-NTF to identify genomic changes linked to carnivorism and adaptation to post-Permian-Triassic extinction environments.

Novel Ser74 of NF-kappaB/CgIkappaBalpha Phosphorylated by MAPK/ERK Regulates Temperature Adaptation in Oysters

The paper identifies a novel phosphorylation site (Ser74) in oyster NF-kappaB/CgI{kappa}B regulated by MAPK/ERK that mediates thermal adaptation through ubiquitin-proteasome degradation and nuclear translocation of CgREL.

Air-liquid interface exposure of A549 human lung cells to characterize the hazard potential of a gaseous bio-hybrid fuel blend

This study assesses the toxic effects of a KEAA fuel blend on A549 lung cells using air-liquid interface exposure and finds no adverse effects within tested concentrations.

Nephrectomy and high-salt diet inducing pulmonary hypertension and kidney damage by increasing Ang II concentration in rats

This study develops a CKD-PH rat model through 5/6 nephrectomy and high-salt diet, showing increased Ang II and RAAS imbalance, ACE2 downregulation, and metabolic changes linked to pulmonary hypertension.

Epsins oversee smooth muscle cell reprogramming by influencing master regulators KLF4 and OCT4.

This study shows Epsins regulate smooth muscle cell reprogramming by modulating OCT4 and KLF4, with implications for coronary artery disease.

Characterization of DSPE-mPEG raw materials from different vendors reveals differences in impurity profiles and polymer chain length polydispersity

The paper analyzes DSPE-mPEG raw materials from different vendors, finding variations in impurity profiles and polymer chain length polydispersity using mass spectrometry.

The Vk*MYC Mouse Model recapitulates human multiple myeloma evolution and genomic diversity

The paper develops a Vk*MYC mouse model of multiple myeloma that mirrors human disease progression, genomic diversity, and key molecular features.

Unraveling the dynamic transcriptomic changes during the dimorphic transition of Talaromyces marneffei through time-course analysis

This study identifies dynamic transcriptional changes during the dimorphic transition of Talaromyces marneffei using a novel model, DyGAM-NS, and reveals asymmetrical gene expression patterns and regulatory networks.

Comprehensive Characterization of tRNA by Ultra High-Performance Liquid Chromatography High-Resolution Accurate Mass Spectrometry

The paper characterizes tRNA modifications using high-resolution mass spectrometry and identifies novel features in yeast tRNA.

The immune receptor SNC1 monitors helper NLRs targeted by a bacterial effector

The paper shows that SNC1, an immune receptor, guards ADR1-L1 and ADR1-L2 from bacterial effector suppression, enabling plant immunity through sequence diversification and a layered defense system.

Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that comprise distinct phasevarions

This study identifies multiple phase-variable DNA methyltransferases in Actinobacillus pleuropneumoniae, showing their role in regulating phasevarions and pathogenic traits.

Targeting Epsins to Inhibit FGF Signaling while Potentiating TGF-beta Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis

This study identifies epsins as promoters of endothelial-to-mesenchymal transition in atherosclerosis and shows that a therapeutic peptide targeting epsin-FGFR1 interaction reduces EndoMT and atherosclerosis progression.

Monitoring of urban ecological environment including air quality using satellite imagery

This study introduces a new remote sensing index for urban ecological monitoring by integrating air quality data with existing ecological factors, showing improved assessment in Beijing.

Autophagy receptor NDP52 alters DNA conformation to modulate RNA Polymerase II transcription

This study identifies NDP52's role in modulating RNA Polymerase II transcription by altering DNA conformation through direct dsDNA binding and interactions with chromatin regulators.

Alkaliphilus flagellata sp. nov., Butyricicoccus intestinisimiae sp. nov., Clostridium mobile sp. nov., Clostridium simiarum sp. nov., Dysosmobacter acutus sp. nov., Paenibacillus brevis sp. nov., Peptoniphilus ovalis sp. nov., and Tissierella simiarum sp. nov., isolated from monkey feces

The paper describes eight novel bacterial species isolated from cynomolgus monkey feces and provides their taxonomic characterization.

Differential use of multiple genetic sex determination systems in divergent ecomorphs of an African crater lake cichlid

The paper identifies three coexisting sex-determining alleles in two ecomorphs of Astatotilapia calliptera, showing genetic interactions affecting fitness and speciation.

Biphasic Control of Cell Expansion by Auxin Coordinates Etiolated Seedling Development

The paper shows auxin's biphasic control of cell expansion coordinates hypocotyl elongation and apical hook formation in etiolated seedlings.

Processive Dynamics of the Usher Assembly Platform During Uropathogenic Escherichia coli P Pilus Biogenesis

The paper determines cryo-EM structures of the activated PapC usher during P pilus biogenesis, revealing processive steps and conformational dynamics.

Lossless and Contamination-Free Digital PCR

This paper introduces CLEAR-dPCR, a lossless and contamination-free digital PCR technology that improves accuracy and dynamic range compared to existing platforms.

Transient protein accumulation at the center of the T cell antigen presenting cell interface drives efficient IL-2 secretion

The paper investigates the role of the central supramolecular signaling cluster (cSMAC) in T cell activation by manipulating adaptor proteins and showing its impact on IL-2 secretion.

Split Selectable Markers

This paper introduces split selectable markers to enable selection of multiple unlinked transgenes in lentiviral transgenesis and CRISPR/Cas biallelic knock-ins.