Author

J. Audet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1 Immunology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Bello· 3 shared D. Kobasa· 3 shared H. Wood· 3 shared J. E. Strong· 3 shared K. Tierney· 3 shared L. Garnett· 3 shared M. Chan· 3 shared N. Tailor· 3 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. Bello

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components

N. I. Callaghan, L. J. Durland, W. Chen, U. Kuzmanov, M. Z. Miranda, Z. Mirzaei, R. G. Ireland, E. Y. Wang, K. Wagner, M. M. Kim, J. Audet, P. Santerre, A. O. Gramolini, F. Billia, M. Radisic, , C. A. Simmons

This study develops a novel medium for iPSC-derived cardiomyocytes using differential evolution to enhance maturation, validated through multiomic analysis.

bioRxiv · Oct 10, 2022Bioengineering

Validation and Establishment of a SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a pre-screening tool for the Plaque Reduction Neutralization Test

J. Merluza, J. Ung, K. Makowski, A. Robinson, K. J. Manguiat, N. Mueller, J. Audet, J. C.-y. Chen, J. E. Strong, H. Wood, A. Bello

bioRxiv · Sep 13, 2022 · PreprintScientific Communication & Education

An S1 subunit vaccine and combination adjuvant (COVAC-1) elicits robust protection against SARS-CoV-2 challenge in African green monkeys

L. Garnett, K. Tran, M. Chan, K. Tierney, Z. Schiffman, J. Audet, J. Lew, C. Meilleur, M. Chan, K. Manguiat, N. Tailor, R. Vendramelli, Y. Deschambault, G. Beaudoin-Bussieres, C. Bourassa, , D. Falzarano

COVAC-1, an S1 subunit vaccine with adjuvant, protects African green monkeys from SARS-CoV-2 challenge by reducing viral load and pathology in the respiratory tract.

bioRxiv · Jun 16, 2022 · PreprintMicrobiology

North American deer mice are susceptible to SARS-CoV-2

B. D. Griffin, M. Chan, N. Tailor, E. J. Mendoza, A. Leung, B. M. Warner, A. T. Duggan, E. Moffat, S. He, L. Garnett, K. N. Tran, L. Banadyga, A. Albietz, K. Tierney, J. Audet, , D. Kobasa

This study shows North American deer mice can be infected and transmit SARS-CoV-2, suggesting they may serve as a potential reservoir for the virus.

Nature Communications · Jun 14, 2021Peer-reviewedMicrobiology

Exposure route, sex, and age influence disease outcome in a golden Syrian hamster model of SARS-CoV-2 infection

B. D. Griffin, B. M. Warner, M. Chan, E. J. Mendoza, N. Tailor, L. Banadyga, A. Leung, S. He, A. S. Boese, J. Audet, W. Cao, E. Moffat, L. Garnett, K. Tierney, K. N. Tran, , D. Kobasa

This study investigates how exposure route, sex, and age affect SARS-CoV-2 pathogenesis in golden Syrian hamsters, finding significant differences in disease outcomes.

bioRxiv · Jun 12, 2021 · PreprintMicrobiology

LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants

K. Westendorf, S. Zentelis, L. Wang, D. Foster, P. Vaillancourt, M. Wiggin, E. Lovett, R. van der Lee, J. Hendle, A. Pustilnik, J. M. Sauder, L. Kraft, Y. Hwang, R. W. Siegel, J. Chen, , Ramamurt

This paper identifies LY-CoV1404, a potent SARS-CoV-2 neutralizing antibody effective against multiple variants, including Omicron and Delta, due to its conserved epitope and resistance to common mutations.

bioRxiv · Apr 30, 2021Immunology