Author

J. Edgar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. Arrieta· 1 shared A. D. Shandling· 1 shared A. Ellebedy· 1 shared A. Merits· 1 shared A. Randall· 1 shared A. Raskin· 1 shared A. Remmington· 1 shared A. Teng· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperImmunology

A. Arrieta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

J. Clark, I. Hoxie, D. Adelsberg, I. Sapse, R. Andreata-Santos, J. Yong, F. Amanat, J. Tcheou, A. Raskin, G. Singh, I. Gonzalez-Dominguez, J. Edgar, S. Bournazos, W. Sun, J. M. Carreno, , F. Krammer

This study identifies non-neutralizing antibodies from vaccinated individuals that protect against SARS-CoV-2 in animal models, highlighting their role through Fc-mediated effector functions and conserved epitope binding.

bioRxiv · Feb 28, 2024Immunology

Age-Associated Weaker Immunity to Coronaviruses is Characteristic of Children that Develop Multisystem Inflammatory Syndrome following SARS-CoV-2 Infection

D. Camerini, A. Arrieta, A. Randall, J. Gach, H. Maecker, J. Hoang, K. Imfeld, S. Osborne, C. Enriquez, C. Hung, J. Edgar, A. D. Shandling, V. Huynh, A. Teng, J. Pablo, , D. Nugent

The paper compares antibody and cytokine responses between MIS-C patients and convalescent COVID-19 children, finding weaker antibody responses and elevated proinflammatory cytokines in MIS-C.

bioRxiv · Aug 28, 2023 · PreprintImmunology

Cryptic prophages within a Streptococcus pyogenes genotype emm4 lineage

A. Remmington, S. Haywood, J. Edgar, C. E. Turner

This study identifies a cryptic prophage lineage in emm4 Streptococcus pyogenes isolates, showing gene loss and reduced inducibility compared to other strains.

bioRxiv · May 19, 2020Microbiology

Pan-viral protection against arboviruses by targeting inoculation site-based skin macrophages

S. R. Bryden, M. Pingen, D. R. Lefteri, J. Major, L. Delang, S. Jacobs, R. Abdelnabi, J. Neyts, J. Miltenburg, H. Khalid, A. Tuplin, A. Merits, E. Pondeville, J. Edgar, G. J. Graham, , C. McKimmie

The paper shows that activating innate immune responses at the mosquito bite site, specifically targeting skin-resident macrophages, can inhibit systemic arbovirus dissemination and improve clinical outcomes.

bioRxiv · Mar 4, 2019Immunology