Author

J. Noel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. A. Lane· 1 shared A. A. Melo· 1 shared A. B. Oliveira· 1 shared A. Chen· 1 shared A. Garcia-Sastre· 1 shared A. Hassan· 1 shared A. K. Shalek· 1 shared A. Patel· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

A. A. Lane

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single-cell Multiomics Reveals Clonal T-cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm

E. A. DePasquale, D. Ssozi, M. Ainciburu, J. Good, J. Noel, M. Villanueva, C. Couturier, A. K. Shalek, S. F. Aranki, H. R. Mallidi, G. K. Griffin, A. A. Lane, P. van Galen

This study uses single-cell multiomics to analyze T-cell responses in BPDCN, finding upregulated IFNA and downregulated TNFA pathways, along with T-cell exhaustion and clonotype expansion.

bioRxiv · Dec 1, 2021Immunology

Cryo-electron tomography reveals structural insights into the membrane binding and remodeling activity of dynamin-like EHDs

A. A. Melo, T. Sprink, J. Noel, E. Vazquez Sarandeses, C. van Hoorn, J. Loerke, C. M.T. Spahn, O. Daumke

The paper uses cryo-electron tomography to determine the structure of EHD4 filaments on a membrane, revealing insights into their remodeling activity.

bioRxiv · Sep 20, 2021 · PreprintBiophysics

SMOG 2 and OpenSMOG: Extending the limits of structure-based models

A. B. Oliveira, V. Contessoto, A. Hassan, S. Byju, A. Wang, Y. Wang, E. G. Dodero Rojas, U. Mohanty, J. Noel, J. N. Onuchic, P. C. Whitford

This paper introduces SMOG 2 and OpenSMOG, extending structure-based models to handle large biomolecular systems with enhanced customization and integration with OpenMM.

bioRxiv · Aug 15, 2021Biophysics

Gating Mechanism of β-Ketoacyl-ACP Synthases

J. Mindrebo, A. Patel, W. Kim, T. Davis, A. Chen, T. Bartholow, J. La Clair, J. A. McCammon, J. Noel, M. Burkart

The paper investigates the gating mechanism in β-ketoacyl-ACP synthases using structural and dynamic analyses to reveal how substrate discrimination occurs during catalytic reactions.

bioRxiv · May 21, 2019 · PreprintBiochemistry

Discovery Of UFO Proteins: Human-Virus Chimeric Proteins Generated During Influenza Virus Infection

Y. Ma, M. Angel, G. Wang, J. S. Y. Ho, N. Zhao, J. Noel, N. Moshkina, J. Gibbs, J. Wei, B. Rosenberg, J. Johnson, M. Chang, Z. Peralta, N. Krogan, C. Benner, , I. Marazzi

The paper identifies host-virus chimeric proteins, called UFOs, generated during influenza virus infection through the translation of viral 5UTRs using host transcripts.

bioRxiv · Apr 8, 2019 · PreprintMicrobiology