Hippo effector, Yorkie, is a Tumor Suppressor in Select Drosophila Squamous Epithelia
R. Bhattacharya, J. Kumari, S. Banerjee, J. Tripathi, N. Mohan, P. SINHA
This study shows that Yki signaling suppresses PI3K/Akt/TOR in Drosophila squamous epithelia, preventing tumor formation, and that its loss leads to cancer-like changes in multiple tubular organs.
bioRxiv · Oct 15, 2023 · PreprintCancer Biology