Author

J. Hur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2 Biophysics· 1 Cell Biology· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 5 Organism:mouse· 5 Research Focus:differential expression· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2

Frequent Co-Authors

K. Guo· 3 shared D. J. K. Yombo· 2 shared N. Khan· 2 shared R. Mathur· 2 shared T. Schmit· 2 shared Z. WangiD· 2 shared A. Lund Da Costa· 1 shared A. T. Ting· 1 shared

Activity by Year

2016-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

K. Guo

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Author profile →

9 papers

Recent·Most cited

RSV infection does not induce EMT

S. N. Talukdar, B. A. McGregor, J. K. Osan, J. Hur, M. Mehedi

This study shows RSV infection does not induce epithelial-mesenchymal transition (EMT) in three in vitro lung models, as evidenced by distinct cellular and transcriptomic changes compared to TGF-β1.

bioRxiv · Mar 13, 2023 · PreprintMicrobiology

Enhanced production of natural shiga toxin by overexpressing A subunit of Stx2e in Stx2e-producing Escherichia coli isolated in South Korea

J. Hur, B. J. Seo, J. H. Yu, S. C. Kim, Y. J. Yu, B. Y. Park, J. H. Park, W. I. Kim

This study enhances Stx2e production in STEC 150229 by overexpressing the A subunit, resulting in higher cytotoxicity against Vero cells.

bioRxiv · Jul 30, 2022 · PreprintMicrobiology

TFAM-dependent mitochondrial integrity in regulatory T cells preserves immune landscape and restrains inflammaging

K. Guo, Z. Wang, J. S. Gill, T. Debnath, B. Bansal, R. Poojary, J. K. Correa, H. Celik, H. Mehta, E. Abrham, Z. Even, M. Rahman, A. Lund Da Costa, S. Jain, X. Wang, , R. Mathur

This study identifies TFAM-dependent mitochondrial integrity in Tregs as critical for preserving immune homeostasis and preventing inflammaging.

bioRxiv · Mar 8, 2022 · PreprintImmunology

The chemokine receptor CXCR3 promotes CD8+ T cell-dependent lung pathology during influenza pathogenesis

K. Guo, D. J. K. Yombo, J. Xu, Z. Wang, T. Schmit, J. Tripathi, J. Hur, J. Sun, M. A. Olszewski, N. Khan

The paper identifies CXCR3-expressing CD8+ T cells as a driver of lung pathology during influenza infection without affecting viral clearance.

bioRxiv · Feb 14, 2022Immunology

Cellular heterogeneity and molecular reprogramming of host response during influenza acute lung injury

K. Guo, D. J. K. Yombo, T. Schmit, Z. Wang, S. Ghosh, V. Sathish, R. Mathur, M. Wu, J. Hur, M. N. Khan

This study uses scRNA-seq to analyze lung cellular heterogeneity and host response during severe influenza infection in mice, identifying key immune and non-immune cell changes and communication dynamics.

bioRxiv · Aug 5, 2021Immunology

Role of Gasdermins in the Biogenesis of Apoptotic Cell-Derived Exosomes

J. Hur, Y. J. Kim, D. A. Choi, D. W. Kang, J. Kim, H. S. Yoo, S. A. Shahriyar, T. Mustajab, D. Y. Kim, Y.-J. Chwae

This study identifies gasdermin-mediated mechanisms in apoptotic exosome biogenesis and shows their role in tumor-induced inflammation.

bioRxiv · Apr 27, 2021Cell Biology

High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss

O.-H. Kim, C. J. Booth, H. S. Choi, J. Lee, J. Kang, J. Hur, H. J. Choi, H. Kim, J.-H. Auh, J.-Y. Cha, Y. J. Lee, C. S. Lee, C. Choi, J.-y. Yang, S.-S. Im, , B.-C. Oh

This study shows that a high-phytate/low-calcium diet causes crystal nephropathies, renal phosphate wasting, and bone loss in rats through tubular dysfunction and altered mineral absorption.

bioRxiv · Oct 29, 2019Physiology

Seed Genome Hypomethylated Regions Are Enriched In Transcription Factor Genes

M. Chen, J.-Y. Lin, J. Hur, J. M. Pelletier, R. Baden, M. Pellegrini, J. J. Harada, R. Goldberg

The paper identifies DNA Methylation Valleys (DMVs) in soybean and Arabidopsis seed genomes, showing they are enriched in transcription factor genes and remain hypomethylated throughout development.

bioRxiv · Jun 27, 2018Plant Biology

Melittin-induced alterations in morphology and deformability of human red blood cells using quantitative phase imaging techniques

J. Hur, K. Kim, S. Lee, H. Park, Y. Park

This study examines melittin's effects on human red blood cells using quantitative phase imaging, revealing morphological, biochemical, and mechanical changes.

bioRxiv · Dec 6, 2016Biophysics