Author

K. Chellappa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

J. A. Baur· 2 shared R. T. Shima· 2 shared A. E. Kane· 1 shared A. Mueller· 1 shared C. A. Thaiss· 1 shared C. Diener· 1 shared C. Duesing· 1 shared C. Jankowski· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. A. Baur

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2 papers

Recent·Most cited

Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner

A. E. Kane, K. Chellappa, M. B. Schultz, M. Arnold, J. Li, J. Amorim, C. Diener, D. Zhu, S. J. Mitchell, P. T. Griffin, X. Tian, C. Petty, R. Conway, K. Walsh, L. Shelerud, , D. A. Sinclair

This study shows that long-term NMN treatment improves healthspan and extends lifespan in female mice but not males, with sex-specific effects on metabolism and microbiome.

bioRxiv · Jun 21, 2024 · PreprintPharmacology & Toxicology

NAD precursors cycle between host tissues and the gut microbiome

K. Chellappa, M. R. McReynolds, W. Lu, X. Zeng, M. Makarov, F. Hayat, S. Mukherjee, Y. R. Bhat, S. R. Lingala, R. T. Shima, H. C. Descamps, T. Cox, L. Ji, C. Jankowski, Q. Chu, , J. A. Baur

The paper shows NAD precursors cycle between host tissues and the gut microbiome to maintain NAD homeostasis.

bioRxiv · Nov 15, 2021Physiology