Author

K. Kunzelmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Baehr· 1 shared A. Budelsky· 1 shared A. Hochheimer· 1 shared A. Leith· 1 shared A. Moretti· 1 shared A. Saalmueller· 1 shared A. Schnell· 1 shared B. Bennett· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Baehr

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Increased pulmonary monocyte infiltration and attenuated phagocytosis defines perinatal dysfunction of innate immunity in Cystic Fibrosis

F. Jaudas, F. Bartenschlager, B. Shashikadze, G. Santamaria, A. Schnell, N. Naumann-Barsch, H. Bruns, S. Y. Graeber, A. Baehr, M. Cambra-Bort, M. Stirm, J. B. Stoeckl, S. Krebs, H. Blum, C. Schulz, , N. Klymiuk

The paper identifies increased monocyte infiltration and reduced phagocytosis in CF lungs at birth, suggesting innate immune dysfunction and the need for early treatment.

bioRxiv · Sep 11, 2023 · PreprintImmunology

Drug repurposing for Cystic Fibrosis: identification of drugs that induce CFTR-independent fluid secretion in nasal organoids

L. W. Rodenburg, L. Delpiano, V. Railean, R. Centeio, M. C. Pinto, S. M. A. Smits, I. S. van der Windt, C. F. J. van Hugten, S. F. B. van Beuningen, R. N. P. Rodenburg, C. K. van der Ent, M. D. Amaral, K. Kunzelmann, M. A. Gray, J. M. Beekman, G. D. Amatngalim

This study identifies 12 FDA-approved drugs that induce CFTR-independent fluid secretion in nasal organoids, offering potential treatment for CF patients unresponsive to CFTR modulators.

bioRxiv · Sep 23, 2022Cell Biology

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide are Potent TMEM16A Antagonists that Fully Bronchodilate Airways

K. Miner, K. Labitzke, B. Liu, P. Wang, K. Henckels, K. Gaida, R. Elliott, J. J. Chen, L. Liu, A. Leith, E. Trueblood, K. Hensley, X.-Z. Xia, O. Homann, B. Bennett, , J. K. Sullivan

This paper identifies niclosamide and nitazoxanide as potent TMEM16A antagonists that fully bronchodilate airways, offering new treatment options for severe asthma and COPD.

bioRxiv · Nov 14, 2018Physiology