Author

L. Barisoni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cell Biology· 1 Genomics· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. E. Alpers· 2 shared S. Jain· 2 shared A. J. Gallan· 1 shared A. Schroeder· 1 shared A. Tata· 1 shared A. Z. Rosenberg· 1 shared Alessia FornoniiD· 1 shared Alicia M. NeuiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersPathology

C. E. Alpers

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Author profile →

5 papers

Recent·Most cited

A user-friendly tool for cloud-based whole slide image segmentation, with examples from renal histopathology

B. R. Lutnick, D. Manthey, J. U. Becker, B. Ginley, K. Moos, J. E. Zuckerman, L. Rodrigues, A. J. Gallan, L. Barisoni, C. E. Alpers, X. Wang, K. Myakala, B. A. Jones, M. Levi, J. B. Kopp, , Kidney Precision Medicine Project

Histo-Cloud is a cloud-based tool for whole slide image segmentation that simplifies access for non-experts, demonstrating its use in renal histopathology.

bioRxiv · Aug 16, 2021Pathology

Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

S. Ide, Y. Kobayashi, K. Ide, S. A. Strausser, S. Herbek, L. L. O'Brien, S. D. Crowley, L. Barisoni, A. Tata, P. R. Tata, T. Souma

The paper shows that ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells, contributing to maladaptive renal repair after severe injury.

bioRxiv · Mar 23, 2021Cell Biology

A Multimodal and Integrated Approach to Interrogate Human Kidney Biopsies with Rigor and Reproducibility: The Kidney Precision Medicine Project

T. M. El-Achkar, M. T. Eadon, R. Menon, B. B. Lake, T. K. Sigdel, T. Alexandrov, S. Parikh, G. Zhang, D. Dobi, K. W. Dunn, E. A. Otto, C. R. Anderton, J. M. Carson, J. Luo, C. Park, , For the Kidney Precision Medicine Project

The paper describes a pipeline for generating 3D molecular atlases of human kidney biopsies using multi-OMICS and imaging technologies, emphasizing quality control and reproducibility across institutions.

bioRxiv · Aug 23, 2020 · PreprintScientific Communication & Education

APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy

L. A. Bruggeman, Z. Wu, L. Luo, S. Madhavan, P. E. Drawz, D. B. Thomas, L. Barisoni, J. F. O'Toole, J. R. Sedor

This study shows that APOL1-G0 protects podocytes from HIV-induced damage in mice, while APOL1-G2 does not provide similar protection.

bioRxiv · Apr 18, 2019Pathology

An eQTL landscape of kidney tissue in human nephrotic syndrome

Christopher E. Gillies, Rosemary K.B. Putler, Rajasree Menon, Edgar A. Otto, Kalyn Yasutake, Viji Nair, Paul Hoover, David Lieb, Shuqiang Li, Sean F. Eddy, Damian Fermin, Michelle T. McNulty, John R. Sedor, Katherine M. Dell, Marleen Schachere, , Cindy Roy

The paper identifies eQTLs in glomerular and tubulointerstitial kidney tissues from nephrotic syndrome patients, finds tissue-specific eQTLs, and integrates them with a GWAS to identify associated genes.

The American Journal of Human Genetics · Jul 26, 2018Peer-reviewedGenomics