M. Burns

Regulation of angiogenesis by endocytic trafficking mediated by cytoplasmic dynein 1 light intermediate chain 1

This study shows that LIC1 and RILPL1/2 restrict angiogenesis by promoting VEGFR2 degradation, and their disruption increases angiogenesis through enhanced Rab11-mediated recycling.

Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4+ T cells as predictors for response to integrin α4β7-blocking therapy in patients with inflammatory bowel disease

Modular Fluorescent Nanoparticle DNA Probes for Detection of Peptides and Proteins

This paper introduces a method to create fluorescent nanoparticle probes using DNA aptamers for detecting peptides and proteins, showing high affinity and stability.

Predicting Moisture Content During Maize Nixtamalization Using Machine Learning with NIR Spectroscopy

This study uses machine learning with NIR spectroscopy to predict maize kernel moisture content during nixtamalization, finding environmental factors and complex genetics influence the trait.

A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.

This study evaluates a recombinant SARS-CoV-2 vaccine in macaques, showing that antigens from the RBD elicit high-titer neutralizing antibodies lasting over 20 weeks.

De novo synthesis and salvage pathway coordinately regulates polyamine homeostasis and determines T cell proliferation and function.

This study shows that polyamine homeostasis in T cells is regulated by de novo synthesis and salvage pathways, affecting proliferation and function, with implications for inflammatory and autoimmune diseases.

APOBEC3A Catalyzes Mutation and Drives Carcinogenesis In Vivo

This study shows APOBEC3A promotes tumorigenesis in mice and supports its role in causing mutations in human cancers.

Prohibitin is a prognostic marker of relapse and therapeutic target to block chemotherapy resistance in Wilms tumor

This study identifies prohibitin as a urine biomarker for Wilms tumor relapse and shows it promotes chemotherapy resistance by disrupting mitochondrial apoptosis.