H. Watanabe

Neuronal and non-neuronal functions of the synaptic cell adhesion molecule, neurexin, in Nematostella vectensis.

This study investigates the functions of neurexins in the cnidarian Nematostella vectensis, revealing both neuronal and non-neuronal roles in synaptic and cell adhesion processes.

Trehalose mediates salinity-stress tolerance in a crustacean

This study shows that trehalose production, mediated by the TPS gene, enables Daphnia magna to tolerate salinity stress, with tolerance linked to native habitat salinity and local adaptation.

Automated escape system: identifying prey's kinematic and behavioral features critical for predator evasion

This study develops an automated escape system to identify prey kinematic and behavioral features critical for predator evasion, showing that escape speed and reaction distance significantly affect predator-prey interactions.

Cnidarian pharyngeal nervous system illustrates prebilaterian neurosecretory regulation of feeding

The paper identifies a cnidarian oral/pharyngeal nervous system with features similar to bilaterian neurosecretory brain centers, suggesting an evolutionary precursor for feeding regulation.

NF-κB Decoy ODN-Loaded Poly lactic-co-glycolic Acid Nanospheres Inhibit Alveolar Ridge Resorption

This study investigates the therapeutic effect of NF-κB decoy ODN-loaded PLGA nanospheres in reducing alveolar ridge resorption after tooth extraction in rats.

Hydrothermal Vent Species Assemblage Networks Identify Regional Connectivity Patterns in the Northwest Pacific

The paper analyzes hydrothermal vent species assemblage networks in the Northwest Pacific to identify regional connectivity patterns and their implications for conservation.

Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea

This study identifies Cyb5r3 downregulation as a mechanism of sulfonylurea failure and shows that a Cyb5r3 activator can reverse this failure in an animal model.

m6A demethylase ALKBH5 promotes tumor cell proliferation by destabilizing IGF2BPs target genes and worsens the prognosis of patients with non-small cell lung cancer

Triple Notch/Tgfβ/FoxO1 blockade converts multiple intestinal sub-lineages into β-like cells and lowers glycemia in diabetic animals

Entamoeba histolytica EHD1 is involved in mitosome-endosome contact

The paper identifies EHD1 as a protein involved in mitosome-endosome contact in Entamoeba histolytica through immunoprecipitation, immunofluorescence, and live imaging.

Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade

This study investigates the self-assembling properties of CAHS1 protein from tardigrades under desiccation conditions, showing it forms hydrogels and condensates that may contribute to desiccation tolerance.

Classical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer

This study identifies distinct lineage states in small cell lung cancer driven by c-Myc and L-Myc, showing their unique roles in molecular subtypes and histology.

Comparison of prokaryotic communities among fields exhibiting different disinfestation effects by anaerobic soil disinfestation

The paper compares prokaryotic communities in soils with different disinfestation effects after anaerobic soil disinfestation, finding specific microbial changes associated with effective disinfestation.

Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma

This study identifies two distinct LUSC subtypes driven by Sox2 partnerships with Brn2 or p63, revealing lineage heterogeneity and potential therapeutic targets.

A combined strategy of neuropeptide predictions and tandem mass spectrometry identifies evolutionarily conserved ancient neuropeptides in the sea anemone Nematostella vectensis