Author

M. B. Beasley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:statistical model· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. H. Rahman· 2 shared A. Lansky· 2 shared A. M. Leader· 2 shared A. Sinha· 2 shared A. Tabachnikova· 2 shared A. Wolf· 2 shared C. A. Powell· 2 shared E. Kenigsberg· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

A. H. Rahman

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Author profile →

4 papers

Recent·Most cited

Spatial positioning and matrix programs of cancer-associated fibroblasts promote T cell exclusion in human lung tumors

J. A. Grout, P. Sirven, A. M. Leader, S. Maskey, E. Hector, I. Puisieux, F. Steffan, E. Cheng, N. Tung, M. Maurin, R. Vaineau, L. Karpf, M. Plaud, M. Casanova-Acebes, A. Tabachnikova, , H. Salmon

The paper identifies two CAF subsets in human lung tumors that promote T cell exclusion through distinct matrix programs and spatial organization.

bioRxiv · Jan 20, 2022Cancer Biology

Classical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer

A. S. Patel, S. Yoo, R. Kong, T. Sato, A. Sinha, L. Bao, M. Fridrikh, K. Emoto, G. Nudelman, C. A. Powell, M. B. Beasley, J. Zhu, H. Watanabe

This study identifies distinct lineage states in small cell lung cancer driven by c-Myc and L-Myc, showing their unique roles in molecular subtypes and histology.

bioRxiv · Nov 3, 2020Cancer Biology

CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations

A. M. Leader, J. A. Grout, C. Chang, B. Maier, A. Tabachnikova, L. Walker, A. Lansky, J. LeBerichel, N. Malissen, M. Davila, J. Martin, G. Magri, K. Tuballes, Z. Zhoa, F. Petralia, , M. Merad

The paper analyzes CITEseq data from NSCLC lesions to identify an immune cell activation module linked to tumor antigen load and TP53 mutations.

bioRxiv · Jul 16, 2020 · PreprintImmunology

Epigenomic profiling discovers trans-lineage SOX2 partnerships driving tumor heterogeneity in lung squamous cell carcinoma

T. Sato, S. Yoo, R. Kong, M. Fridrikh, A. Sinha, P. Chandramani-Shivalingappa, A. Patel, O. Nagano, T. Masuko, M. B. Beasley, C. A. Powell, J. Zhu, H. Watanabe

This study identifies two distinct LUSC subtypes driven by Sox2 partnerships with Brn2 or p63, revealing lineage heterogeneity and potential therapeutic targets.

bioRxiv · Jun 12, 2019Cancer Biology