M. Bender

Public Health Response to Pan-Resistant Pseudomonas aeruginosa Sequence Type 309 with Tandem Guiana Extended Spectrum Beta Lactamases Genetic Characterization and In Vivo Efficacy Assessment using Translational Murine Model.

The paper identifies a pan-resistant Pseudomonas aeruginosa strain with GES in California and assesses its treatment using a translational murine model.

Cellular, Molecular, and Enzymatic Signatures ofThrombi are Vascular Bed-Dependent

This study compares cellular and enzymatic features of arterial and venous thrombi from different vascular beds, finding distinct molecular profiles and enzyme activities linked to vascular remodeling.

Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping.

This study shows ex vivo anticoagulants affect platelet biomechanics and demonstrates their impact on mechanophenotyping in a MYH9-related disorder.

Optogenetic manipulation of cGMP highlights PDE5 as the predominant cGMP-hydrolyzing PDE in megakaryocytes

The paper uses optogenetics to manipulate cGMP levels in megakaryocytes and identifies PDE5 as the main enzyme regulating cGMP.

Reduced platelet forces underlie impaired hemostasis in mouse models of MYH9-related disease

This study shows that reduced platelet forces in Myh9 mutant mice cause impaired hemostasis, which can be improved by tranexamic acid.

Strong functional divergence of tropical reef fish assemblages along the global diversity gradient

The paper shows that tropical reef fish assemblages show strong trait divergence along the global diversity gradient, influenced by body size and diet, and linked to past climatic isolation of reefs.

Top-down engineering of complex communities by directed evolution

This study develops a modeling framework to explore directed evolution strategies for engineering complex microbial communities, identifying effective methods to enhance their stability and functionality.