Author

M. Brenner

Ernst Strüngmann Institute for Neuroscience

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Microbiology· 1 Neuroscience· 1

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Organism:mouse· 2

Frequent Co-Authors

S. Raychaudhuri· 3 shared A. Filer· 2 shared J. Turner· 2 shared M. Coles· 2 shared A. A. Herskovits· 1 shared A. Croft· 1 shared A. Gohla· 1 shared A. Haber· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

S. Raychaudhuri

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Author profile →

6 papers

Recent·Most cited

Promise and Limits of Hierarchical Dynamical RNNs for Individualized Resting-State fMRI

Carlotta Barkhau, Keyvan Mahjoory, M. Brenner, Ramona Leenings, C. Pellengahr, L. Fisch, N.R. Winter, Maximilian Konowski, Hamidreza Jamalabadi, Tilo T. J. Kircher, M. Junghoefer, U. Dannlowski, T. Hahn

This paper evaluates hierarchical shallow piecewise-linear RNNs for modeling individual resting-state fMRI, finding they capture functional connectivity but have limited predictive power for phenotypic variables.

Neuroscience Applied · Jan 1, 2026Peer-reviewedNeuroscience

7,8-Dihydroxyflavone is a direct inhibitor of pyridoxal phosphatase

M. Brenner, C. Zink, L. Witzinger, A. Keller, K. Hadamek, S. Bothe, M. Neuenschwander, C. Villmann, J. P. von Kries, H. Schindelin, E. Jeanclos, A. Gohla

This study identifies 7,8-dihydroxyflavone as a direct inhibitor of pyridoxal phosphatase, increasing PLP levels in mouse hippocampal neurons and validating PDXP as a druggable target.

bioRxiv · Oct 4, 2023Biochemistry

A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease

T. Thomas, C. Rich-Griffin, M. Pohin, M. Friedrich, D. Aschenbrenner, J. Pakpoor, A. Jainarayanan, A.-I. Voda, R. Sanches Peres, E. Nee, D. Sathananthan, D. Kotliar, J. Turner, S. Nayar, F. Zhang, , C. Buckley

This study creates a therapeutic atlas of anti-TNF treatment in IBD, showing disease- and therapy-specific cellular changes and identifying IFN signalling as a potential target for JAK inhibition.

bioRxiv · May 5, 2023Immunology

Listeria monocytogenes TcyKLMN cystine/cysteine transporter facilitates glutathione synthesis and virulence gene expression

A. A. Herskovits, M. Brenner, S. Freidman, A. Haber, I. Borovok, N. Sigal, O. Lewinson

bioRxiv · Sep 7, 2021Microbiology

Pathologically distinct fibroblast subsets drive inflammation and tissue damage in arthritis

A. Croft, J. Campos, K. Jansen, J. Turner, J. Marshall, M. Attar, L. Savary, H. Perlman, F. Barone, H. McGettrick, D. Fearon, K. Wei, S. Raychaudhuri, I. Lorsunsky, M. Brenner, , C. D. Buckley

The paper identifies two distinct fibroblast subsets in arthritis that drive inflammation or tissue damage, showing their unique roles in disease progression.

bioRxiv · Jul 23, 2018 · PreprintImmunology

A genome-wide innateness gradient defines the functional state of human innate T cells

M. Gutierrez-Arcelus, N. Teslovich, A. R. Mola, H. Kim, S. Hannes, K. Slowikowski, G. F. M. Watts, M. Brenner, S. Raychaudhuri, P. J. Brennan

The paper identifies an innateness gradient in human T cells, showing a trade-off between effector function and proliferative capacity.

bioRxiv · Mar 13, 2018Immunology