Author

S. Lenzini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Mehta· 1 shared E. Zakhem· 1 shared F. Hossen· 1 shared G. B. Kim· 1 shared G. Zhou· 1 shared G.-H. Nam· 1 shared H. Choi· 1 shared H. Joo· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

D. Mehta

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure

S. Kim, Y. K. Kim, S. Kim, Y.-S. Choi, I. Lee, H. Joo, J. Kim, M. Kwon, S. Park, M. K. Jo, Y. Choi, T. D'Souza, J. W. Jung, E. Zakhem, S. Lenzini, , I.-S. Kim

This paper develops SIRPα-expressing extracellular vesicles from engineered stem cells to treat acute liver failure by resolving necroptosis and promoting liver regeneration, showing reduced liver damage and improved survival in models.

bioRxiv · May 24, 2024Bioengineering

Tension sensing by FAK governs nuclear mechanotransduction, endothelial transcriptome and fate

M. Z. Akhter, P. Yazbeck, M. Tauseef, M. Anwar, F. Hossen, S. Datta, V. Vellingiri, J. C. Joshi, N. Srivastava, S. Lenzini, G. Zhou, J. Lee, M. K. Jain, J.-W. Shin, D. Mehta

This study shows that FAK-mediated tension sensing in endothelial cells regulates nuclear mechanotransduction, transcriptome, and cell fate, crucial for maintaining a restrictive endothelial barrier.

bioRxiv · Apr 24, 2023 · PreprintCell Biology