Author

M. Steain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:proteomics· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

A. Aggarwal· 3 shared J. A. Triccas· 3 shared A. Stella· 2 shared C. Ashley· 2 shared C. Counoupas· 2 shared J. Mackay· 2 shared K. Patel· 2 shared N. Bhattacharyya· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. Aggarwal

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Neutralising antibodies against the SARS-CoV-2 Delta variant induced by Alhydroxyquim-II-adjuvanted trimeric spike antigens

C. Counoupas, P. Pino, A. Stella, C. Ashley, H. Lukeman, N. Bhattacharyya, T. Tada, S. Anchisi, C. Metayer, J. Martinis, A. Aggarwal, B. Dcosta, J. Kint, M. Wurm, N. Landau, , J. A. Triccas

This study shows that Alhydroxiquim-II-adjuvanted trimeric spike antigens induce high-titre, cross-variant neutralising antibodies against SARS-CoV-2 in animal models.

bioRxiv · Aug 18, 2021Microbiology

Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein using mRNA Display

A. Norman, C. Franck, M. Christie, P. Hawkins, K. Patel, A. Ashhurst, A. Aggarwal, J. K. Low, R. Siddiquee, C. Ashley, M. Steain, J. A. Triccas, S. G. Turville, J. Mackay, T. Passioura, R. J. Payne

The paper identifies cyclic peptide ligands to the SARS-CoV-2 spike protein RBD using mRNA display, finding six high-affinity molecules with nanomolar dissociation constants.

ACS Central Science · Jun 23, 2021Peer-reviewedBiochemistry

A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice

C. Counoupas, M. D. Johnson, A. Stella, D. H. Nguyen, A. Ferguson, A. Aggarwal, N. Bhattacharyya, A. Grey, K. Patel, R. Siddiquee, E. L. Stewart, O. Hutchings, C. Feng, N. G. G. Hansbro, U. Palendira, , J. A. Triccas

A BCG-adjuvanted vaccine provides sterilizing immunity against SARS-CoV-2 in mice, with high neutralizing antibody titers and Th1 responses.

bioRxiv · Dec 10, 2020 · PreprintMicrobiology

Varicella zoster virus encodes a viral decoy RHIM to inhibit cell death

M. Steain, M. O. D. G. Baker, C. L. L. Pham, Y. Gambin, E. Sierecki, B. P. McSharry, S. Avdic, B. Slobedman, M. Sunde, A. Abendroth

This paper identifies a viral RHIM in VZV ORF20 that forms amyloid complexes with ZBP1 to inhibit apoptosis during infection.

bioRxiv · Mar 12, 2020Microbiology