Author

M. T. Lewno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

H. Su· 2 shared J. Li· 2 shared J. Liu· 2 shared P. Wu· 2 shared X. Wang· 2 shared B. Pan· 1 shared C. Wang· 1 shared J. Fang· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

H. Su

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2 papers

Recent·Most cited

Cell BiologyCirculation: Heart FailurePeer-reviewedAug 1, 2020

The COP9 Signalosome Suppresses Cardiomyocyte Necroptosis

P. Xiao, C. Wang, M. T. Lewno…·X. Wang

This study shows that Cops8/CSN deficiency in cardiomyocytes leads to necroptosis via the RIPK1-RIPK3 pathway, with Nrf2 and redox stress playing key roles.

DOI 10.1161/circheartfailure.120.006996

mouseproteomics

𝕏 PostBluesky

Cell BiologyCirculation ResearchPeer-reviewedJul 31, 2020

The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction

B. Pan, N. Parajuli, Z. Tian…·X. Wang

This study identifies the Mocln1-calcineurin-TFEB-p62 pathway as mediating cardiac macroautophagy activation due to proteasomal malfunction.

DOI 10.1161/circresaha.119.316007

mouseproteomics

𝕏 PostBluesky