M. Tenbusch

Single-cell analysis reveals lasting immunological consequences of influenza infection and respiratory immunisation in the pig lung

This study uses single-cell RNA sequencing and flow cytometry to analyze immunological changes in pig lungs after influenza infection or vaccination, revealing lasting effects on immune cell populations and function.

Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation

This study shows alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation, which disrupts actin binding and reduces migration and immune responses.

Protective mucosal immunity against SARS-CoV-2 after heterologous systemic RNA-mucosal adenoviral vector immunization

This study shows that intranasal adenoviral vector boosts after mRNA priming enhance mucosal immunity and protection against SARS-CoV-2 in mice.

A pair of non-competing neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model

The paper identifies two clusters of non-competing neutralizing antibodies against SARS-CoV-2 that protect mice from infection and weight loss.

SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in the requirements for receptor expression and proteolytic activation

This study compares the requirements for receptor expression and proteolytic activation in SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion, revealing differences in their dependence on ACE2, TMPRSS2, and metalloproteases.

Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

The paper finds that low interleukin-3 levels predict increased severity and mortality in SARS-CoV-2 infections and shows IL-3 promotes antiviral pDC recruitment.