Author

N. Berry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 5 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

D. Fernig· 5 shared C. Winstanley· 3 shared D. M. Foulkes· 3 shared K. McLean· 3 shared S. B. Kaye· 3 shared C. Eyers· 2 shared C. Wells· 2 shared D. Byrne· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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5 shared papersBiochemistry

D. Fernig

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

A phospholipase assay screen identifies synergistic inhibitors of the P. aeruginosa toxin ExoU

D. M. Foulkes, K. McLean, A. Hermann, J. Johnson, C. Winstanley, N. Berry, D. Fernig, S. B. Kaye

This study identifies synergistic inhibitors of P. aeruginosa ExoU through a phospholipase assay screen, showing reduced cytotoxicity in vitro and in corneal assays.

bioRxiv · Feb 21, 2022 · PreprintBiochemistry

SARS-CoV-2 Virus like Particles produced by a single recombinant baculovirus generate potent neutralizing antibody that protects against variant challenge

E. Sullivan, P.-y. Sung, W. Wu, N. Berry, S. Kempster, D. Ferguson, N. Almond, I. M. Jones, P. Roy

This study generates SARS-CoV-2 virus-like particles using baculovirus expression, showing they induce neutralizing antibodies and protect against variant challenge in a hamster model.

bioRxiv · Nov 29, 2021 · PreprintMicrobiology

Impact of fluoroquinolones and aminoglycosides on P. aeruginosa virulence factor production and cytotoxicity

D. M. Foulkes, K. McLean, M. Sloniecka, D. Byrne, A. S. Haneef, C. Winstanley, N. Berry, D. Fernig, S. B. Kaye

This study evaluates the effects of fluoroquinolones and aminoglycosides on P. aeruginosa T3SS expression and cytotoxicity in corneal epithelial cell models, finding tobramycin inhibits T3SS and cytotoxicity while fluoroquinolones upregulate T3SS and enhance cytotoxicity.

bioRxiv · Oct 11, 2021Biochemistry

Evaluation of ExoU inhibitors in a Pseudomonas aeruginosa scratch infection assay

D. M. Foulkes, K. McLean, J. Harris, A. Haneef, D. Fernig, C. Winstanley, N. Berry, S. B. Kaye

This study evaluates ExoU inhibitors in a Pseudomonas aeruginosa scratch infection model, showing their effectiveness in reducing cytotoxicity when combined with antimicrobials.

bioRxiv · Jun 24, 2020 · PreprintBiochemistry

New tools for carbohydrate sulphation analysis: Heparan Sulphate 2-O-sulphotranserase (HS2ST) is a target for small molecule protein kinase inhibitors

D. P. Byrne, Y. Li, K. Ramakrishnan, I. Barsukov, E. Yates, C. Eyers, D. Papy-Garcia, S. Chantepie, V. Pagadala, J. Liu, C. Wells, D. Drewry, W. Zuercher, N. Berry, D. Fernig, P. A. Eyers

This paper introduces a new non-radioactive assay for HS2ST activity using a synthetic fluorescent substrate and identifies protein kinase inhibitors that inhibit HS2ST-catalyzed sulphation.

bioRxiv · Apr 6, 2018Biochemistry

New tools for evaluating protein tyrosine sulphation: Tyrosyl Protein Sulphotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

P. Eyers, D. Byrne, P. Ngamlert, Y. Li, K. Ramakrishnan, C. Eyers, C. Wells, D. Drewry, W. Zuercher, N. Berry, D. Fernig

The paper develops a non-radioactive assay to quantify tyrosine sulphation by TPST1 and TPST2 and identifies RAF kinase inhibitors as potential TPST inhibitors.

bioRxiv · Apr 6, 2018Biochemistry