Author

A. Levine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2

Frequent Co-Authors

D. Grushko· 2 shared E. Cohen· 2 shared A. A. Baccarelli· 1 shared A. Bousvaros· 1 shared A. Rodgers· 1 shared A. Rudensky· 1 shared A. Shyu· 1 shared A. Strang· 1 shared

Activity by Year

2016-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 4 mutual co-author links

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2 shared papersCell Biology

D. Grushko

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Novel modification of Luminex assay for characterization of extracellular vesicle populations in biofluids.

O. V. Volpert, E. Gershun, K. Elgart, V. Kalia, H. Wu, A. A. Baccarelli, E. Eren, D. Kapogiannis, A. Verma, A. Levine, E. Eitan

This paper introduces a novel Luminex-based immunoassay for multiplexed detection of EV surface proteins without requiring EV purification, demonstrating its ability to differentiate EVs from erythrocytes, macrophages, and neurons.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Glycolysis Fuels Phosphoinositide 3-Kinase Signaling to Bolster T Cell Immunity

K. Xu, N. Yin, M. Peng, E. Stamatiades, A. Shyu, P. Li, X. Zhang, M. Do, Z. Wang, K. Capistrano, C. Chou, A. Levine, A. Rudensky, M. Li

This study shows that glycolysis fuels PI3K signaling in CD8+ T cells, linking metabolic reprogramming to T cell immunity and suggesting therapeutic targets for infectious diseases and cancer.

Science · Jan 22, 2021Peer-reviewedImmunology

Temporal Requirements of SKN-1/NRF as a Regulator of Lifespan and Proteostasis in Caenorhabditis elegans

E. Cohen, D. Grushko, A. Levine, H. Boocholez

This study identifies the temporal role of SKN-1 in regulating lifespan and proteostasis in C. elegans, showing its importance during late larval development through early adulthood.

bioRxiv · Nov 24, 2020Cell Biology

Treatment-Specific Composition of Gut Microbiota Is Associated with Disease Remission in a Pediatric Crohn’s Disease Cohort

D. Sprockett, N. Fischer, R. S. Boneh, D. Turner, J. Kierkus, M. Sladek, J. Escher, E. Wine, B. Yerushalmi, J. A. Dias, R. Shaoul, M. Kori, S. Snapper, S. Holmes, A. Bousvaros, , D. A. Relman

This study examines how gut microbiota changes with metronidazole and metronidazole plus azithromycin treatments in pediatric Crohn’s disease and finds that microbiota profiles can predict disease remission.

bioRxiv · May 19, 2019Microbiology

Gene Expression Modulation by the Linker of Nucleoskeleton and Cytoskeleton Complex Contributes to Proteostasis

A. Levine, D. Grushko, E. Cohen

This study shows that the LINC complex modulates proteostasis by affecting ubiquitination and degradation rates in nematodes, linking it to aging-associated proteotoxicity.

bioRxiv · Feb 27, 2019Cell Biology

Immune profiling of cord blood after prolonged rupture of membranes.

E. Tsaliki, C. Turner, C. Venturini, C. Kam, A. Strang, S. Bailey, A. Rodgers, A. Levine, B. Chain, N. Simpson, E. Riley, N. Field, P. Brocklehurst, M. Noursadeghi

This study identifies transcriptomic changes in cord blood following prolonged rupture of membranes, suggesting immune responses to potential in utero infections.

bioRxiv · Oct 16, 2018 · PreprintImmunology

Simultaneous cell traction and growth measurements using light

S. Sridharan, Y. Li, L. Foucard, H. Majeed, B. Bhaduri, A. Levine, K. Kilian, G. Popescu

This paper introduces a method to simultaneously measure cell traction forces and growth using light-based imaging, showing that mesenchymal stem cells exert different forces during osteogenesis and adipogenesis.

bioRxiv · Oct 20, 2017Cell Biology

Mouse T cell repertoires as statistical ensembles: overall characterization and age dependence

Z. Sethna, Y. Elhanati, C. S. Dudgeon, C. G. Callan, A. Levine, T. Mora, A. Walczak

The paper analyzes T cell repertoires in mice to show age-related increases in VDJ recombination diversity and similar selection effects in thymus and blood.

bioRxiv · Nov 10, 2016Immunology