Author

P. Lakshmanane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

A. Grifoni· 2 shared A. Sette· 2 shared D. Weiskopf· 2 shared I. Castillo· 2 shared M. T. Heise· 2 shared A. E. Whitten· 1 shared A. Frazier· 1 shared A. K. Falconar· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Grifoni

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chikungunya-virus-specific CD4+ T cells are associated with chronic chikungunya viral arthritic disease in humans

J. Chang, R. Agarwal, F. H. Cortes, C. Ha, J. Villalpando, I. Castillo, R. I. Galvez, A. Grifoni, A. Sette, C. M. Romero-Vivas, M. T. Heise, P. Lakshmanane, A. K. Falconar, D. Weiskopf

This study identifies CHIKV-specific CD4+ T cell responses in chronic CHIKVD patients, showing stronger responses and Th17 enrichment compared to resolved infection.

bioRxiv · Nov 20, 2023 · PreprintImmunology

Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

A. Tarke, Y. Zhang, N. Methot, T. N. Narowski, E. Phillips, S. Mallal, A. Frazier, G. Filaci, D. Weiskopf, J. M. Dan, P. Lakshmanane, R. H. Scheuermann, A. Sette, A. Grifoni

This study identifies T cell epitopes and cross-reactivity patterns across common cold coronaviruses, highlighting conservation and limitations in cross-reactivity among subgenera.

bioRxiv · Jan 4, 2023Immunology

Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination

L. E. Adams, S. R. Leist, K. H. Dinnon, A. West, K. L. Gully, E. Anderson, J. F. Loome, E. Madden, J. Powers, A. Schaefer, S. Sarkar, I. Castillo, J. Maron, R. P. McNamara, H. L. Bertera, , R. S. Baric

This study shows that non-neutralizing antibodies targeting FcR4 and spike S2 provide cross-protection against sarbecoviruses after alphavirus vector vaccination.

bioRxiv · Nov 28, 2022Microbiology

The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase

P. M. Walden, P. Lakshmanane, M. Halili, B. Heras, G. King, A. E. Whitten, J. L. Martin

This study characterizes the structure and function of DsbA2 from Wolbachia pipientis, revealing it as a homotrimeric disulfide isomerase with distinct activity compared to other DsbA enzymes.

bioRxiv · Sep 11, 2018Biochemistry