High throughput functional screening for next generation cancer immunotherapy using droplet-based microfluidics
Y. Wang, R. Jin, B. Shen, N. Li, H. Zhou, W. Wang, Y. Zhao, M. Huang, P. Fang, S. Wang, P. Mary, R. Wang, P. Ma, R. Li, Y. Cao, , h. Zhang
This paper develops a droplet-based microfluidics platform for high-throughput functional antibody screening, identifying potent cancer immunotherapeutics like CD40 agonists and anti-Her2/anti-CD3 bispecific antibodies.
bioRxiv · Nov 25, 2020Cancer Biology