A biomechanical switch promotes lysosomal remodelling and exocytosis in keloid fibroblasts
R. Ross, Y. Guo, R. N. Walker, D. Bergamaschi, T. J. Shaw, J. T. Connelly
This study shows keloid fibroblasts have heightened cytoskeletal tension and lysosomal exocytosis in response to mechanical cues, altering ECM remodeling.
bioRxiv · Nov 1, 2023Cell Biology