C. Jamora

Partial alopecia area retains bulge hair follicle progenitor cells in Indian androgenetic alopecia patients

The paper identifies that progenitor cells persist in partially bald areas of Indian AGA patients but are absent in completely bald areas, suggesting a timeframe for therapeutic intervention.

Poly (A) Binding Protein 2 is critical for stem-progenitor differentiation during regeneration in the planarian Schmidtea mediterranea.

This study shows that PABP2 is essential for neoblast differentiation during planarian regeneration, as its deficiency disrupts progenitor formation and tissue organization.

Evaluation of melanocyte stem cell population in vitiliginous skin pre- and post-narrow-band UVB phototherapy

This study evaluates melanocyte stem cell and immune cell changes in vitiligo patients before and after narrow-band UVB phototherapy, finding increased MelSC re-population and reduced CD3+ T-cells.

Dermal wound healing contribution of aqueous extracts of Acalypha indica, Calotropis gigantea, Bacopa monnieri and their combination

This study evaluates the wound healing efficacy of aqueous extracts of three medicinal plants and their combination in mice, showing faster closure and improved tissue remodeling.

Angiopoietin-like protein 2 mediates vasculopathy driven fibrogenesis in a mouse model of systemic sclerosis

This study identifies Angptl2 as a driver of fibrotic vasculopathy in a mouse model of SSc and shows that inhibiting its effects can reduce fibrogenesis.

Bacopa monnieri phytochemicals regulate fibroblast cell migration via modulation of focal adhesions

This study shows Bacopa monnieri extract enhances fibroblast migration through focal adhesion modulation, improving wound healing.

Extracellular caspase-1 regulates hair follicle stem cell migration during wound-healing

This study identifies extracellular Caspase-1 as a chemoattractant that drives hair follicle stem cell migration during wound healing.

Niacinamide enhances cathelicidin mediated SARS-CoV-2 membrane disruption

This study shows niacinamide enhances LL37's ability to disrupt SARS-CoV-2 membranes, suggesting it could improve AMP-based therapies for COVID-19.

Mindin differentially regulates fibroblast subpopulations via distinct members of the Src family kinases during fibrogenesis.

This study shows Mindin regulates distinct fibroblast subpopulations through different Src family kinases during fibrosis and cancer.

Mindin is essential for cutaneous fibrogenesis in a new mouse model of systemic sclerosis

This study identifies Mindin as a key driver of fibrosis in a new mouse model of systemic sclerosis, showing its role in inducing inflammation and collagen production in fibroblasts.

The initiation of the wound healing program is regulated by the convergence of mechanical and epigenetic cues

This study identifies how mechanical tension in the epidermis triggers DNA methylation changes via DNMT3a, leading to gene expression shifts that initiate wound healing.

Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of the matricellular protein Mindin

This study identifies Snail's role in maintaining stem/progenitor state in skin epithelial cells and carcinomas via Mindin-mediated autocrine signaling.

Mechanical Instability of Adherens Junctions Overrides Intrinsic Quiescence of Hair Follicle Stem Cells

This study shows that vinculin loss in murine skin disrupts adherens junctions, leading to loss of bulge stem cell quiescence through impaired force generation and YAP1 retention.