R. Woods

Mono-phosphorylation at Ser4 of Barrier-to-autointegration Factor (Banf1) significantly reduces its DNA binding capability by inducing critical changes in its local conformation and DNA binding surface

This study investigates how mono-phosphorylation at Ser4 of Banf1 disrupts its DNA binding by altering its conformation and binding surface through molecular modeling and simulations.

Rising daptomycin resistance in Enterococcus faecium across a hospital system occurred via rampant recurrent evolution and occasional transmission between patients.

This study shows that daptomycin resistance in Enterococcus faecium increased due to recurrent mutations and occasional transmission between patients in a hospital system.

Oral cholestyramine prevents enrichment of diverse daptomycin-resistance mutations in intestinal Enterococcus faecium

This study shows that cholestyramine prevents the enrichment of daptomycin-resistant Enterococcus faecium mutations in the gut when administered before or after daptomycin treatment.

Gut microbiome features are associated with sepsis onset and outcomes

This study finds that gut microbiome features, including increased Enterococcus and total bacterial abundance, and decreased butyrate-producing bacteria, are associated with sepsis onset and mortality.

Landscape and Selection of Vaccine Epitopes in SARS-CoV-2

This study identifies vaccine epitopes in SARS-CoV-2 by combining computational T cell epitope prediction, B cell epitope mapping, and manufacturability criteria to propose candidate peptides for further testing.

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium.

The paper shows neutrophil microvesicles deliver miR-155 to atheroprone endothelium, promoting vascular inflammation and atherosclerosis in mice.