Author

S. A. Summers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

W. L. Holland· 2 shared A. M. Nuotio-Antar· 1 shared A. R. Cox· 1 shared A. Vivoli· 1 shared A.-L. Castell· 1 shared B. A. Kiapparettu· 1 shared B. Chaurasia· 1 shared C. Bensard· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

W. L. Holland

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability

P. M. Masschelin, P. Saha, S. A. Ochsner, A. R. Cox, K. H. Kim, J. B. Felix, R. Sharp, X. Li, L. Tan, J. H. Park, L. Wang, V. Putluri, P. L. Lorenzi, A. M. Nuotio-Antar, Z. Sun, , S. M. Hartig

This study shows that vitamin B2 deficiency impairs PPAR regulation of fasting glucose, and PPAR agonists can rescue this defect.

bioRxiv · Oct 16, 2022Physiology

Very Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

A.-L. Castell, A. Vivoli, T. S. Tippetts, I. Robillard Frayne, V. S. Moulle, M. Ruiz, J. Ghislain, C. Des Rosiers, W. L. Holland, S. A. Summers, V. Poitout

This study shows that oleate induces β-cell proliferation in rats via unsaturated very long-chain sphingolipids, mediated by ACBP and ELOVL1.

bioRxiv · Jul 16, 2021Cell Biology

Serine Palmitoyltransferase Controls Stemness of Intestinal Progenitors

S. A. Summers, B. Chaurasia, Y. Li, V. Kaddai, J. L. Wilkerson, J. A. Maschek, J. Cox, P. Wei, C. Bensard, P. J. Meikle, H. Clevers, J. Shayman, Y. Hirabayashi, W. L. Holland, J. Rutter

The paper shows that serine palmitoyltransferase (SPT) modulates intestinal stem cell homeostasis by promoting stemness through sphingolipid production and PPAR-alpha activation, linking diet to cancer risk.

bioRxiv · Dec 3, 2020 · PreprintCell Biology