Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
R. Ballaro, S. Pareek, J. Lee, H. Patel, P. Tirumala, G. Liu, K. Hayek, H. Savage, B. Guerrouahen, A. Ngo-Huang, N. Parker, M. H. Katz, M. Petzel, F. McAllister, R. Wright, , K. Schadler
This study shows aerobic exercise improves PDAC vascular function and chemotherapy efficacy via S1PR1 signaling in tumor endothelial cells.
bioRxiv · Feb 14, 2024 · PreprintCancer Biology
C. L. Chappell, K. L. Hoffman, P. L. Lorenzi, L. Tan, J. Petrosino, R. Gibbs, D. Muzny, H. Doddapaneni, M. C. Ross, V. K. Menon, A. Surathu, S. J. Javornik Cregeen, A. G. Reyes, P. C. Okhuysen
The paper measures tryptophan metabolites in fecal samples from healthy individuals and links them to bacterial abundance and predicted microbial sources.
bioRxiv · Dec 20, 2023 · PreprintMicrobiology
Y. Wang, V. V. Kulkarni, J. Pantaleon Garcia, M. M. Leiva-Juarez, D. L. Goldblatt, F. Gulraiz, J. Chen, S. R. Donepudi, P. L. Lorenzi, H. Wang, L.-J. Wong, M. J. Tuvim, S. E. Evans
The paper shows that CpG ODNs interact with mitochondrial VDAC1 to induce antimicrobial ROS in lung epithelial cells, offering a new therapeutic strategy for pneumonia without antibiotics.
bioRxiv · Jan 19, 2023 · PreprintImmunology
P. M. Masschelin, P. Saha, S. A. Ochsner, A. R. Cox, K. H. Kim, J. B. Felix, R. Sharp, X. Li, L. Tan, J. H. Park, L. Wang, V. Putluri, P. L. Lorenzi, A. M. Nuotio-Antar, Z. Sun, , S. M. Hartig
This study shows that vitamin B2 deficiency impairs PPAR regulation of fasting glucose, and PPAR agonists can rescue this defect.
bioRxiv · Oct 16, 2022Physiology
M. L. Baek, J. Lee, K. E. Pendleton, M. J. Berner, E. B. Goff, L. Tan, S. A. Martinez, T. Wang, M. D. Meyer, B. Lim, J. P. Barrish, W. Porter, P. L. Lorenzi, G. V. Echeverria
This study identifies how residual triple negative breast cancer cells adapt mitochondrial structure and function to survive chemotherapy, showing that DNA-damaging agents promote mitochondrial fusion and OXPHOS, which can be targeted with OPA1 inhibitors.
bioRxiv · Feb 25, 2022Cancer Biology
Z. Schwabkey, D. Wiesnoski, C.-C. Chang, W.-B. Tsai, D. Pham, S. S. Ahmed, T. Hayase, M. R. Ortega Turrubiates, R. K. El-Himri, C. A. Sanchez, E. Hayase, A. C. Frenk Oquendo, T. Miyama, T. M. Halsey, B. E. Heckel, , E. J. Shpall
The paper links diet-derived metabolites and mucus to fever after cytotoxic cancer treatment by showing how Akkermansia muciniphila affects colonic mucus and inflammation.
bioRxiv · Sep 18, 2021Microbiology
F. Puca, F. Yu, C. Bertolacci, P. Pettazzoni, A. Carugo, E. Huang-Hobbs, J. Liu, C. Zanca, F. Carbone, E. Del Poggetto, J. Gumin, P. Dasgupta, S. Seth, F. F. Lang, E. Sulman, , G. Draetta
This study identifies MCAD as a critical enzyme for fatty acid metabolism in GBM, showing its essential role in preventing mitochondrial damage and apoptosis.
bioRxiv · Sep 28, 2020 · PreprintCancer Biology
F. Liu, X. Zuo, Y. Liu, Y. Deguchi, M. J. Moussalli, W. Chen, P. Yang, B. Wei, P. L. Lorenzi, S. Gao, J. C. Jaoude, A. Mehdizadeh, L. A. Valentin, D. Wei, I. Shureiqi
This study shows that 15-LOX-1 metabolism of LA in PI3P reduces LRP5 membrane levels, inhibits Wnt/β-catenin signaling, and suppresses colorectal tumorigenesis in mice.
bioRxiv · Aug 29, 2019Cancer Biology
J. M. Molkentine, T. N. Fujimoto, T. Horvath, A. J. Grossberg, A. Deorukhkar, E. L. G. Samuel, W. K. Chan, P. L. Lorenzi, R. Dantzer, J. M. Tour, K. A. Mason, C. Taniguchi
This study shows oral WR-2721 provides effective radioprotection and survival benefits after lethal radiation by selectively protecting the intestine.
bioRxiv · Mar 27, 2018Cancer Biology