Author

S. Lynham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:differential expression· 1 Organism:E. coli· 1

Frequent Co-Authors

G. H. Carpenter· 2 shared A. Angbohang· 1 shared A. Margariti· 1 shared A. Sagar· 1 shared A. Shah· 1 shared B. Dorgan· 1 shared C. J. C. Edwards-Gayle· 1 shared D. Iuga· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

G. H. Carpenter

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A novel nested gene Aff3ir participates in vascular remodelling by enhancing endothelial cell differentiation in mice

Y. Zhao, M. Ehteramyan, Y. Li, X. Bai, L. Huang, Y. Gao, A. Angbohang, X. Yang, S. Lynham, A. Margariti, A. Shah, Y. Tao, T. Cai, T. Li, M. Zhang, L. Zeng

This study identifies Aff3ir as a novel gene involved in endothelial cell differentiation by enhancing vascular stem/progenitor cell differentiation in mice.

bioRxiv · Dec 9, 2023 · PreprintCell Biology

MX2 viral substrate breadth and inhibitory activity are regulated by protein phosphorylation

G. Betancor, M. E. M. Bangham, J. K. Jeon, K. Sha, S. Lynham, J. M. Jimenez Guardeno, M. H. Malim

This paper identifies key phosphorylation sites in MX2 that regulate its antiviral activity and substrate specificity, showing that hypermorphic mutants can inhibit HIV-1 and resistant retroviruses.

bioRxiv · Jan 24, 2022Microbiology

Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation

P. Corsini, S. Wang, S. Rehman, K. Fenn, A. Sagar, S. Sirovica, L. Cleaver, C. J. C. Edwards-Gayle, G. Mastroianni, B. Dorgan, L. M. Sewell, S. Lynham, D. Iuga, W. T. Franks, J. Jarvis, , J. A. Garnett

This study investigates the structure and function of SslE in E. coli biofilm maturation, showing its role in aggregate formation and exopolysaccharide distribution under acidic conditions.

bioRxiv · Feb 7, 2021Microbiology

Identification of Chlorophyll a-b Binding Protein AB96 as a novel TGFbeta1 binding agent.

S. Lynham, F. Grundland Freile, N. M. Puri, N. O'Reilly, G. H. Mitchell, T. Wells, M. Willcox, R. Beatson

The paper identifies chlorophyll a-b binding protein AB96 as a plant-derived protein that binds to active TGFbeta1, suggesting potential therapeutic applications.

bioRxiv · Aug 20, 2020Immunology

Agonists of orally expressed TRP channels stimulate salivary secretion and modify the salivary proteome

J. W. Houghton, G. H. Carpenter, J. Hans, M. Pesaro, S. Lynham, G. B. Proctor

This study investigates how TRP channel agonists affect salivary secretion and proteome composition, finding that nonivamide and menthol increase saliva flow and alter protein profiles.

bioRxiv · Jun 17, 2020Physiology