Author

N. Bah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. Moore· 3 shared E. Mugarza· 2 shared J. Downward· 2 shared S. Rana· 2 shared A. de Castro· 1 shared A. Fearns· 1 shared A. Rodgers· 1 shared B. Aylan· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

C. Moore

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CRISPR/Cas9 screen identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer

J. Boumelha, A. de Castro, N. Bah, H. Cha, S. de Carne Trecesson, S. Rana, P. Anastasiou, E. Mugarza, C. Moore, R. Goldstone, P. East, K. Litchfield, S.-H. Lee, M. Molina-Arcas, J. Downward

The paper identifies KRAS-induced COX-2 as a driver of immunotherapy resistance in lung cancer through CRISPR/Cas9 screening and shows targeting COX-2 enhances immune checkpoint blockade efficacy.

bioRxiv · Apr 13, 2023Cancer Biology

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

C. Bussi, T. Heunis, E. Pellegrino, E. M. Bernard, N. Bah, M. Silva Dos Santos, P. Santucci, B. Aylan, A. Rodgers, A. Fearns, J. Mitschke, C. Moore, J. I. MacRae, M. Greco, T. Reinheckel, , M. G. Gutierrez

This study shows lysosomal damage leads to mitochondrial proteome changes and metabolic reprogramming in macrophages, affecting immune responses to infections.

bioRxiv · Aug 9, 2022Cell Biology

Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow

F. van Maldegem, K. Valand, M. Cole, H. Patel, M. Angelova, S. Rana, E. Colliver, K. Enfield, N. Bah, V. Tsang, E. Mugarza, C. Moore, P. Hobson, D. Levi, M. Molina, , J. Downward

The paper optimises an imaging mass cytometry workflow to study TME remodelling in mouse models after KRAS G12C inhibitor treatment.

bioRxiv · Feb 2, 2021Cancer Biology