Author

S. Sangwan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

L. Wang· 2 shared P. Walter· 2 shared A. A. Anand· 1 shared A. Anand· 1 shared A. Deal· 1 shared A. F. Brilot· 1 shared A. M. Smith· 1 shared A. N. Rizo· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

L. Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling

R. Lawrence, S. Shoemaker, A. Deal, S. Sangwan, A. Anand, L. Wang, S. Marqusee, P. Walter

The paper identifies a Switch-Helix in eIF2B that allosterically regulates ISR signaling and is conserved across species.

bioRxiv · Dec 22, 2022 · PreprintBiochemistry

A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response.

A. Subramanian, L. Wang, T. Moss, M. Voorhies, S. Sangwan, E. Stevenson, E. H. Pulido, S. Kwok, N. J. Krogan, D. L. Swaney, S. N. Floor, A. Sil, P. Walter, S. Mukherjee

This paper identifies SidI, a Legionella toxin that mimics tRNA, glycosylates the translation machinery, and triggers a ribotoxic stress response leading to cell death.

bioRxiv · Jun 10, 2022Cell Biology

Mapping QTLs for phenotypic and morpho-physiological traits related to grain yield under late sown conditions in wheat (Triticum aestivum L.)

Y. K. Pankaj, L. Pal, R. Nagarajan, K. S. Gill, V. Kumar, S. Sangwan, S. Panigrahi, R. Kumar

This study maps QTLs for grain yield and related traits under normal and late sown conditions in wheat, identifying a major QTL on chromosome 3B associated with heat tolerance.

bioRxiv · Jun 17, 2021Plant Biology

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

M. Schoof, B. Faust, R. A. Saunders, S. Sangwan, V. V. Rezelj, N. Hoppe, M. Boone, C. Billesboelle, C. Puchades, C. M. Azumaya, H. T. Kratochvil, M. Zimanyi, I. Deshpande, J. Liang, S. Dickinson, , Barile-H

This paper develops a potent synthetic nanobody that neutralizes SARS-CoV-2 by locking its Spike protein in an inactive conformation, enabling aerosol delivery as a prophylactic or therapeutic agent.

bioRxiv · Aug 8, 2020Biochemistry