T. Kinoshita

This study shows that Ikzf1 associates with Foxp3 to repress genes in Treg cells, and disrupting this association leads to autoimmunity and enhanced tumor immunity.

This paper presents an automated image analysis pipeline for quantifying stomatal aperture in Arabidopsis thaliana leaves using brightfield microscopy images.

The paper shows that CD73 and ALP sequentially hydrolyze FAD to riboflavin, which is then taken up by cells, and this process is impaired in GPI-deficient cells.

This study shows photosynthesis-dependent activation of PM H+-ATPase in Arabidopsis leaves enhances nitrate uptake, linking photosynthesis and nitrogen metabolism.

This study shows F-actin is essential for polarized secretion of attractants in Arabidopsis synergid cells, affecting pollen tube guidance.

The paper examines microplastic contamination in commercial fish from coastal and offshore waters near Kyushu, Japan, finding higher prevalence and larger sizes in pelagic species compared to demersal ones.

The paper examines temporal changes in MITE TE transcripts during rice endosperm development and finds dynamic up- and downregulation, with some directionally controlled transcripts.

The paper identifies CLPTM1L as a lipid scramblase essential for translocating glucosaminyl-phosphatidylinositol across the ER membrane during GPI biosynthesis.

The paper identifies Cubam receptor-mediated endocytosis and cathepsin L proteolysis as mechanisms for maternal nutrient absorption in the pseudoplacenta of a viviparous teleost fish.

The paper shows that trichome cells in Arabidopsis detect mechanical stimuli from raindrops, triggering calcium waves that activate immune responses against pathogens.

The paper identifies two small molecules that oppositely regulate the Arabidopsis circadian clock by altering period length, revealing their mode of action through genetic mutants.

The paper investigates the effects of nanocarbon molecules on Arabidopsis thaliana transcriptomes and identifies a gene upregulated by these molecules.

The paper identifies B3GALT4's dual role in GPI and glycosphingolipid biosynthesis and shows ER-associated degradation suppresses GPI biosynthesis when GPI transfer to proteins is defective.

This study develops a potent CK1 inhibitor, AMI-331, for plant research by optimizing a lead compound through structure-activity relationship studies.

This study identifies AIF-PNH as a disease caused by germline and somatic mutations in PIGT, leading to complement activation and inflammasome-mediated IL-1β secretion, which is treatable with eculizumab.

This study shows that pathogen-induced pH changes regulate plant growth and defense by modulating cellulose synthesis and fungal pathogenicity through COMPANION OF CELLULOSE SYNTHASE proteins.

This study shows that the FACT complex facilitates DME-mediated DNA demethylation at heterochromatin during Arabidopsis reproduction by enabling access to GC-rich, nucleosome-dense regions.