Author

T. Levade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Fougerat· 2 shared A. Montagner· 2 shared A. Polizzi· 2 shared B. Tramunt· 2 shared C. Postic· 2 shared F. Lasserre· 2 shared H. Guillou· 2 shared L. Gamet-Payrastre· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. Fougerat

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

T. Xu, R. Heon-Roberts, T. Moore, P. Dubot, X. Pan, T. Guo, C. W. Cairo, R. Holley, B. Bigger, T. Durcan, T. Levade, J. Ausseil, B. Amilhon, A. Gorelik, B. Nagar, , A. V. Pshezhetsky

This study shows that reduced NEU1 activity in neurological MPS leads to hypersialylation of brain glycoproteins, contributing to CNS pathology through disrupted synaptogenesis and behavior.

bioRxiv · Apr 26, 2024 · PreprintBiochemistry

p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

M. Regnier, A. Polizzi, T. Fougeray, A. Fougerat, P. Perrier, K. Anderson, Y. Lippi, S. Smati, C. Lukowicz, F. Lasserre, E. Fouche, M. Huillet, C. Rives, B. Tramunt, C. Naylies, , H. Guillou

This study investigates the role of p110alpha in hepatocyte signaling, showing its critical impact on liver gene expression and its rewiring in MASLD.

bioRxiv · Jan 9, 2024 · PreprintCell Biology

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity

A. Fougerat, G. Schoiswohl, A. Polizzi, M. Regnier, C. Wagner, S. Smati, T. Fougeray, Y. Lippi, F. Lasserre, V. Melin, B. Tramunt, C. Alkhoury, A. Emile, M. Schupp, P. Gourdy, , H. Guillou

This study shows that adipose tissue lipolysis via ATGL regulates hepatocyte PPARα activity, which is essential for ketone body production, FGF21 secretion, and BAT activation during fasting and cold exposure.

Cell Reports · Jun 1, 2022Peer-reviewedPhysiology