Author

X.-N. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Liu· 2 shared D. Li· 2 shared H.-Y. Yuan· 2 shared K. Zhao· 2 shared L.-Q. Wang· 2 shared Y. Liang· 2 shared Y. Ma· 2 shared A. W. Cheng· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

C. Liu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ALS-causing SOD1 mutations H46R and G85R form similar novel amyloid fibril structures and promote ferroptosis in cells

L.-Q. Wang, Y. Ma, M.-Y. Zhang, H.-Y. Yuan, X.-N. Li, K. Zhao, W. Xia, X. Huang, J. Chen, L. Zou, D. Li, Z. Wang, W. Le, C. Liu, Y. Liang

This study shows that two ALS-causing SOD1 mutations form similar amyloid fibrils that promote ferroptosis in neuronal cells.

Science Advances · Nov 1, 2024Peer-reviewedBiochemistry

Familial prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM

L.-Q. Wang, K. Zhao, H.-Y. Yuan, X.-N. Li, H.-B. Dang, Y. Ma, Q. Wang, C. Wang, Y. Sun, J. Chen, D. Li, D. Zhang, P. Yin, C. Liu, Y. Liang

The paper reports the cryo-EM structure of an amyloid fibril formed by the E196K mutation in human PrP, revealing a distinct conformation compared to wild-type PrP fibrils.

bioRxiv · Feb 18, 2021Biochemistry

C11orf95-RELA Reprograms 3D Epigenome in Supratentorial Ependymoma

J. J. Zhu, N. Jillette, X.-N. Li, A. W. Cheng, C. C. Lau

This study investigates how the C11orf95-RELA fusion protein reprograms the 3D epigenome in supratentorial ependymoma, revealing its role in chromatin state modulation and transcriptional reprogramming.

bioRxiv · Jun 4, 2020Cancer Biology