Author

Z.-N. Choo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Pe'er· 2 shared I. Masilionis· 2 shared L. Mazutis· 2 shared O. Chaudhary· 2 shared R. Chaligne· 2 shared A. Wuest· 1 shared C. Burdziak· 1 shared C. J. Zhao· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

D. Pe'er

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas

C. Burdziak, D. Alonso-Curbelo, T. Walle, F. M. Barriga, J. Reyes, Y. Xie, Z. Zhao, C. J. Zhao, H.-A. Chen, O. Chaudhary, I. Masilionis, Z.-N. Choo, V. Gao, W. Luan, A. Wuest, , D. Pe'er

The paper uses single-cell analysis to show that epigenetic plasticity and cell-cell interactions drive tissue remodeling in early pancreatic cancer.

bioRxiv · Jul 26, 2022Cancer Biology

Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition

W. Karthaus, J. Chan, M. Setty, J. Love, S. Zaidi, Z.-N. Choo, S. Persad, J. LaClair, K. Lawrence, O. Chaudhary, T. Xu, I. Masilionis, L. Mazutis, R. Chaligne, D. Pe'er, C. Sawyers

This study identifies a pharmacological strategy to reverse lineage plasticity in prostate cancer by inhibiting FGFR and Janus kinase pathways.

bioRxiv · Nov 1, 2021 · PreprintCancer Biology