Author

M. Setty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Approach:Bayesian inference· 1

Frequent Co-Authors

D. Pe'er· 3 shared L. Mazutis· 3 shared A. A. Germanos· 1 shared A. C. Hsieh· 1 shared A. E. Cornish· 1 shared A. E. Flores· 1 shared A. G. Sowalsky· 1 shared A. I. Kousa· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

D. Pe'er

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Defining cellular population dynamics at single cell resolution during prostate cancer progression

A. A. Germanos, S. Arora, Y. Zheng, E. T. Goddard, I. M. Coleman, A. T. Ku, S. Wilkinson, R. A. Amezquita, M. Zager, A. Long, Y. C. Yang, J. H. Bielas, R. Gottardo, C. M. Ghajar, P. S. Nelson, , A. C. Hsieh

This study examines prostate cancer progression at single-cell resolution, identifying castration-resistant luminal cells and their role in treatment resistance and tumor heterogeneity.

bioRxiv · Mar 2, 2022Cancer Biology

Age-related epithelial defects limit thymic function and regeneration

A. I. Kousa, L. Jahn, K. Zhao, A. E. Flores, D. Granadier, K. Cooper, J. M. Sheridan, A. Lemarquis, L. Sikkema, K. V. Argyropoulos, J. Tsai, A. Lazrak, K. Nichols, N. Lee, R. Ghale, , M. R. van den Brink

The paper identifies age-related thymic epithelial cell states that impair thymic regeneration and immune function through spatial and single-cell transcriptomics.

bioRxiv · Dec 16, 2021Immunology

Reversal of lineage plasticity in RB1/TP53-deleted prostate cancer through FGFR and Janus kinase inhibition

W. Karthaus, J. Chan, M. Setty, J. Love, S. Zaidi, Z.-N. Choo, S. Persad, J. LaClair, K. Lawrence, O. Chaudhary, T. Xu, I. Masilionis, L. Mazutis, R. Chaligne, D. Pe'er, C. Sawyers

This study identifies a pharmacological strategy to reverse lineage plasticity in prostate cancer by inhibiting FGFR and Janus kinase pathways.

bioRxiv · Nov 1, 2021 · PreprintCancer Biology

Single-cell Map of Diverse Immune Phenotypes Driven by the Tumor Microenvironment

E. Azizi, A. J. Carr, G. Plitas, A. E. Cornish, C. Konopacki, S. Prabhakaran, J. Nainys, K. Wu, V. Kiseliovas, M. Setty, K. Choi, R. M. Fromme, P. Dao, P. T. McKenney, R. C. Wasti, , D. Pe'er

The paper maps immune cell phenotypes in breast cancer using single-cell RNA-seq and identifies continuous tumor-specific expansions driven by environmental cues.

bioRxiv · Apr 2, 2018Immunology