Author

A. Wuest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

S. W. Lowe· 4 shared H.-A. Chen· 3 shared Y.-J. Ho· 3 shared D. Alonso-Curbelo· 2 shared F. J. Sanchez-Rivera· 2 shared S. Tian· 2 shared W. Luan· 2 shared A. Katti· 1 shared

Activity by Year

2022-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCancer Biology

S. W. Lowe

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Author profile →

4 papers

Recent·Most cited

Rapid generation of precision preclinical cancer models using regulatable in vivo base editing

A. Katti, M. Foronda, J. Zimmermann, M. P. Zafra, S. Goswami, E. E. Gardner, B. J. Diaz, J. M. Simon, A. Wuest, W. Luan, M. T. C. Fernandez, A. P. Kadina, J. A. Walker, K. Holden, F. J. Sanchez-Rivera, , L. E. Dow

This study develops a murine system for temporal and regulatable in vivo cytosine base editing to rapidly generate preclinical cancer models with specific SNVs.

bioRxiv · Aug 3, 2022 · PreprintCancer Biology

Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas

C. Burdziak, D. Alonso-Curbelo, T. Walle, F. M. Barriga, J. Reyes, Y. Xie, Z. Zhao, C. J. Zhao, H.-A. Chen, O. Chaudhary, I. Masilionis, Z.-N. Choo, V. Gao, W. Luan, A. Wuest, , D. Pe'er

The paper uses single-cell analysis to show that epigenetic plasticity and cell-cell interactions drive tissue remodeling in early pancreatic cancer.

bioRxiv · Jul 26, 2022Cancer Biology

Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease

J. Leibold, C. Amor, K. M. Tsanov, Y.-J. Ho, F. J. Sanchez-Rivera, J. Feucht, T. Baslan, H.-A. Chen, S. Tian, J. Simon, A. Wuest, J. E. Wilkinson, S. W. Lowe

This study develops somatic mouse models of gastric cancer that replicate human disease subtypes and reveal genotype-specific metastatic patterns and immune interactions.

bioRxiv · Jun 15, 2022Cancer Biology

Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

H.-A. Chen, Y.-J. Ho, R. Mezzadra, J. M. Adrover, R. M. Smolkin, C. Zhu, L. Wei, A. Wuest, S. Tian, X. Li, R. C. Hendrickson, M. Egeblad, D. Alonso-Curbelo, S. W. Lowe

The paper shows senescent cells enhance immune surveillance by remodeling their surface proteome to better sense and respond to environmental signals like IFN-gamma.

bioRxiv · Jun 4, 2022Cancer Biology