Author

A. Antonopoulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Dell· 3 shared R. Laing· 2 shared S. M. Haslam· 2 shared A. A. Morrison· 1 shared A. Addhya· 1 shared A. E. Friedman· 1 shared A. Filer· 1 shared A. I. Davie· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersImmunology

A. Dell

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A mixed amplicon metabarcoding and sequencing approach for surveillance of drug resistance to levamisole and benzimidazole in Haemonchus spp.

E. K. Francis, A. Antonopoulos, M. E. Westman, J. McKay-Demeler, R. Laing, J. Slapeta

The paper develops a mixed amplicon sequencing approach to detect drug resistance in Haemonchus spp., finding higher prevalence of benzimidazole resistance than levamisole resistance.

bioRxiv · May 14, 2023 · PreprintMicrobiology

Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus

A. Antonopoulos, S. Doyle, D. J. Bartley, A. A. Morrison, R. Kaplan, S. Howell, C. Neveu, V. Busin, E. Devaney, R. Laing

This study develops an allele-specific PCR assay to detect the S168T SNP in acr-8, a marker of levamisole resistance in Haemonchus contortus, and validates it in laboratory and field samples.

bioRxiv · Apr 8, 2022Microbiology

Efficient Inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc

S.-S. Wang, V. del Solar, X. Yu, A. Antonopoulos, A. E. Friedman, K. Agarwal, M. Garg, S. M. Ahmed, A. Addhya, M. Nasirikenari, J. T. Lau, A. Dell, S. M. Haslam, S.-G. Sampathkumar, S. Neelamegham

This paper demonstrates that Ac5GalNTGc is a potent inhibitor of O-glycan biosynthesis, effectively reducing O-glycan elongation and modulating leukocyte functions.

bioRxiv · Dec 13, 2020Biochemistry

High mannose N-glycans on red blood cells as phagocytic ligands, mediating both sickle cell anaemia and resistance to malaria

H. Cao, A. Antonopoulos, S. Henderson, H. Wassall, J. Brewin, A. Masson, J. Shepard, G. Konieczny, B. Patel, M.-L. Williams, A. I. Davie, M. Forrester, L. Hall, B. Minter, D. Tampakis, , M. A. Vickers

bioRxiv · Nov 26, 2020 · PreprintImmunology

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in Rheumatoid Arthritis.

Y. Wang, A. Khan, A. Antonopoulos, L. Bouche, C. D. Buckley, A. Filer, K. Raza, K. Ping-Li, B. Tolusso, E. Gremese, M. Kurowska-Stolarska, S. Alivernini, A. Dell, S. M. Haslam, M. A. Pineda

This study shows that reduced α2-6 sialylation in synovial fibroblasts contributes to a pro-inflammatory phenotype in RA by altering glycosylation pathways.

bioRxiv · Mar 8, 2020Immunology