A. Rajaraman

An NKX-COUP-TFII genomic code for mucosal vascular addressins and organ morphogenesis

The paper identifies a genomic code involving NKX-COUP-TFII elements that regulate mucosal vascular addressin expression and organ morphogenesis.

Deciphering the role of mucosal immune responses and cervicovaginal microbiome in resistance to HIV infection in HIV-exposed seronegative (HESN) women

This study identifies elevated antiviral cytokines, immunoglobulins, and specific immune cell subsets in HESN women, along with increased bacterial diversity and Gardnerella spp abundance in the cervicovaginal microbiome, suggesting protective mechanisms against HIV.

Development of follicular dendritic cells in lymph nodes depends on retinoic acid mediated signaling

This study shows retinoic acid signaling is essential for generating follicular dendritic cells in lymph nodes, while blocking lymphotoxin signaling prevents fibroblastic reticular cell development.

A molecular map of lymph node blood vascular endothelium at single cell resolution

The paper maps the molecular diversity of lymph node blood vascular endothelial cells at single-cell resolution, identifying novel subsets and their roles in immune cell recruitment and vascular homeostasis.

Improving personalized prediction of cancer prognoses with clonal evolution models

This study develops a computational framework to predict cancer progression using mutator phenotypes derived from tumor phylogenies, showing improved predictive power over traditional clinical and driver-centric features.