Author

A. Samanta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Biophysics· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

K. W. Huynh· 2 shared R. A. Pumroy· 2 shared T. E. T. Hughes· 2 shared T. Rohacs· 2 shared V. Y. Moiseenkova-Bell· 2 shared Z. H. Zhou· 2 shared A. Alonso· 1 shared A. Mondal· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

K. W. Huynh

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

G6PD deficiency mediated impairment of iNOS and lysosomal acidification affecting phagocytotic clearance in microglia in response to SARS-CoV-2

A. Mondal, S. Munan, I. Saxena, S. Mukherjee, P. Upadhyay, N. Gupta, W. Dar, A. Samanta, S. Singh, S. Pati

This study shows that G6PD deficiency in microglia impairs iNOS-mediated NO production and lysosomal acidification, leading to reduced phagocytosis of SARS-CoV-2 and increased COVID-19 severity.

bioRxiv · Dec 12, 2023Cell Biology

Hypothalamic Protein Profiling from Mice Subjected to Social Defeat Stress

S. Mitra, G. S. Sameer Kumar, A. Samanta, S. S. Thakur

This study identifies stress-induced protein changes in the hypothalamus of mice subjected to social defeat stress using iTRAQ proteomics, highlighting potential biomarkers for depression.

bioRxiv · Jan 9, 2023 · PreprintAnimal Behavior & Cognition

A biomimetic liver model recapitulating bio-physical properties and tumour stroma interactions in hepatocellular carcinoma

C. Calitz, N. Pavlovic, J. Rosenquist, C. Zagami, A. Samanta, F. Heindryckx

This paper develops a 3D biomimetic HCC model that mimics fibrotic stroma and vasculature, showing drug resistance and metastasis formation in vitro.

bioRxiv · Apr 30, 2020 · PreprintCancer Biology

The Hex-Maze: A previous knowledge and schema task for mice

A. Alonso, L. Bokeria, J. van der Meij, A. Samanta, R. Eichler, P. Spooner, I. Navarro Lobato, L. Genzel

The paper introduces a spatial navigation task for mice, the Hex-Maze, to study how previous knowledge (schema) influences learning and memory consolidation over time.

bioRxiv · Mar 4, 2020 · PreprintAnimal Behavior & Cognition

Molecular mechanism of TRPV2 channel modulation by cannabidiol

R. A. Pumroy, A. Samanta, Y. Liu, T. E. T. Hughes, S. Zhao, Y. Yudin, K. W. Huynh, Z. H. Zhou, T. Rohacs, S. Han, V. Y. Moiseenkova-Bell

This study determines the structure of TRPV2 bound to cannabidiol, revealing a unique binding site and the role of the S4-S5 linker in channel gating.

bioRxiv · May 24, 2019Biophysics

Structural insights on TRPV5 gating by endogenous modulators

T. E. T. Hughes, R. A. Pumroy, A. T. Yazici, M. A. Kasimova, E. C. Fluck, K. W. Huynh, A. Samanta, S. Molugu, Z. H. Zhou, V. Carnevale, T. Rohacs, V. Y. Moiseenkova-Bell

The paper determines TRPV5 structures with endogenous modulators PI(4,5)P2 and CaM, revealing their mechanisms of activation and inhibition.

bioRxiv · Jul 31, 2018Biophysics