Author

A. Wen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Shi· 2 shared Q. Song· 2 shared W. Lin· 2 shared Y. Feng· 2 shared Z. Feng· 2 shared B. Ledbetter· 1 shared C. B. Wall· 1 shared C. Ricci· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

J. Shi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural insights into transcription regulation of the global virulence factor PhoP from Mycobacterium tuberculosis

J. Shi, Q. Song, Z. Feng, A. Wen, T. Liu, L. Xu, Z. Ye, S. Xu, F. Gao, L. Xiao, J. Zhu, K. Das, G.-P. Zhao, Y. Feng, W. Lin

This study determines cryo-EM structures of PhoP-dependent transcription complexes in Mtb to elucidate its dual role as activator and repressor in stress adaptation.

bioRxiv · May 16, 2024 · PreprintMicrobiology

An expanded genetic toolkit for inducible expression and targeted gene silencing in Rickettsia parkeri

J. McGinn, A. Wen, D. L. Edwards, D. M. Brinkley, R. L. Lamason

This paper develops inducible gene expression and CRISPRi-mediated gene knockdown systems in Rickettsia parkeri to study its infectious life cycle.

bioRxiv · Mar 15, 2024 · PreprintMicrobiology

Structural insights into transcription activation mechanism of the global regulator GlnR from actinobacteria

W. Lin, J. Shi, Z. Feng, J. Xu, F. Li, Y. Zhang, A. Wen, F. Wang, Q. Song, L. Wang, S. Wang, Y. Feng

This paper reports the crystal and cryo-EM structures of GlnR-DNA and GlnR-TAC complexes, revealing the transcription activation mechanism of GlnR in actinobacteria.

bioRxiv · Jan 9, 2023 · PreprintBiochemistry

Shifting Baselines: Physiological legacies contribute to the response of reef coral to frequent heat waves

C. B. Wall, C. Ricci, A. Wen, B. Ledbetter, D. Klinger, L. Mydlarz, R. D. Gates, H. Putnam

This study shows that repeated coral bleaching events alter physiological traits and immune responses, creating legacies that affect future thermal stress resilience in reef corals.

bioRxiv · Apr 23, 2020 · PreprintEcology